Sharp VS - Search Results

1

(S)-N-{3-[1-cyclopropyl-1-(2,4-difluoro-phenyl)-ethyl]-1H-indol-7-yl}-methanesulfonamide: a potent, nonsteroidal, functional antagonist of the mineralocorticoid receptor.

Bell MG, Gernert DL, Grese TA, Belvo MD, Borromeo PS, Kelley SA, Kennedy JH, Kolis SP, Lander PA, Richey R, Sharp VS, Stephenson GA, Williams JD, Yu H, Zimmerman KM, Steinberg MI, Jadhav PK. Bell MG, et al. Among authors: sharp vs. J Med Chem. 2007 Dec 27;50(26):6443-5. doi: 10.1021/jm701186z. Epub 2007 Nov 27. J Med Chem. 2007. PMID: 18038968

2

Enantiomeric separation of mineralocorticoid receptor (hMR) antagonists using the Chiralcel OJ-H HPLC column with novel polar cosolvent eluent systems.

Sharp VS, Kennedy JH, Belvo MD, Williams JD, Risley DS, Seest EP. Sharp VS, et al. Chirality. 2006 Jun;18(6):437-45. doi: 10.1002/chir.20269. Chirality. 2006. PMID: 16634131

3

Comparison of separation efficiency of early phase active pharmaceutical intermediates by steady state recycle and batch chromatographic techniques.

Kennedy JH, Belvo MD, Sharp VS, Williams JD. Kennedy JH, et al. Among authors: sharp vs. J Chromatogr A. 2004 Aug 13;1046(1-2):55-60. doi: 10.1016/j.chroma.2004.06.103. J Chromatogr A. 2004. PMID: 15387170

4

Development of analytical and preparative chromatographic separations of novel growth hormone secretagogue compounds.

Kennedy JH, Bowers JL, Dodge JA, Lugar CW, Shepherd TA, Sharp VS. Kennedy JH, et al. Among authors: sharp vs. J Chromatogr A. 2000 Mar 3;872(1-2):75-84. doi: 10.1016/s0021-9673(99)01286-8. J Chromatogr A. 2000. PMID: 10749488

5

Investigation of the mechanism of racemization of litronesib in aqueous solution: unexpected base-catalyzed inversion of a fully substituted carbon chiral center.

Baertschi SW, Jansen PJ, Montgomery RM, Smith WK, Draper JR, Myers DP, Houghton PG, Sharp VS, Guisbert AL, Zhuang H, Watkins MA, Stephenson GA, Harris TM. Baertschi SW, et al. Among authors: sharp vs. J Pharm Sci. 2014 Sep;103(9):2797-2808. doi: 10.1002/jps.23918. Epub 2014 Mar 14. J Pharm Sci. 2014. PMID: 24633856

6

Enantiomeric separation of dansyl amino acids using macrocyclic antibiotics as chiral mobile phase additives by narrow-bore high-performance liquid chromatography.

Sharp VS, Letts MN, Risley DS, Rose JP. Sharp VS, et al. Chirality. 2004 Mar;16(3):153-61. doi: 10.1002/chir.20002. Chirality. 2004. PMID: 14770411

7

High performance liquid chromatographic enantioseparation development and analytical method characterization of the carboxylate ester of evacetrapib using an immobilized chiral stationary phase with a non-conventional eluent system.

Sharp VS, Gokey MA, Wolfe CN, Rener GA, Cooper MR. Sharp VS, et al. J Chromatogr A. 2015 Oct 16;1416:83-93. doi: 10.1016/j.chroma.2015.09.013. Epub 2015 Sep 6. J Chromatogr A. 2015. PMID: 26365911

8

Stereoselective high-performance liquid chromatography and analytical method characterization of evacetrapib using a brush-type chiral stationary phase: a challenging isomeric separation requiring a unique eluent system.

Sharp VS, Stafford JD, Forbes RA, Gokey MA, Cooper MR. Sharp VS, et al. J Chromatogr A. 2014 Oct 10;1363:183-90. doi: 10.1016/j.chroma.2014.03.048. Epub 2014 Mar 27. J Chromatogr A. 2014. PMID: 24725472

9

Evaluation of the macrocyclic antibiotic LY333328 as a chiral selector when used as a mobile phase additive in narrow bore HPLC.

Sharp VS, Risley DS. Sharp VS, et al. Chirality. 1999;11(1):75-81. doi: 10.1002/(SICI)1520-636X(1999)11:1<75::AID-CHIR13>3.0.CO;2-7. Chirality. 1999. PMID: 9914654

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