Kondo T - Search Results

1

Design and synthesis of DPP-IV inhibitors lacking the electrophilic nitrile group.

Kondo T, Nekado T, Sugimoto I, Ochi K, Takai S, Kinoshita A, Hatayama A, Yamamoto S, Kishikawa K, Nakai H, Toda M. Kondo T, et al. Bioorg Med Chem. 2008 Feb 15;16(4):1613-31. doi: 10.1016/j.bmc.2007.11.031. Epub 2007 Nov 17. Bioorg Med Chem. 2008. PMID: 18039579

2

Synthesis, further biological evaluation and pharmacodynamics of newly discovered inhibitors of TNF-alpha production.

Matsui T, Kondo T, Nakatani S, Omawari N, Sakai M, Mori H, Ogata A, Kato J, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: kondo t. Bioorg Med Chem. 2003 Sep 1;11(18):3937-43. doi: 10.1016/s0968-0896(03)00409-7. Bioorg Med Chem. 2003. PMID: 12927854

3

Design and synthesis of long-acting inhibitors of dipeptidyl peptidase IV.

Kondo T, Sugimoto I, Nekado T, Ochi K, Ohtani T, Tajima Y, Yamamoto S, Kawabata K, Nakai H, Toda M. Kondo T, et al. Bioorg Med Chem. 2007 Apr 1;15(7):2715-35. doi: 10.1016/j.bmc.2007.01.033. Epub 2007 Jan 20. Bioorg Med Chem. 2007. PMID: 17292611

4

Design and synthesis of new potent dipeptidyl peptidase IV inhibitors with enhanced ex vivo duration.

Kondo T, Nekado T, Sugimoto I, Ochi K, Takai S, Kinoshita A, Tajima Y, Yamamoto S, Kawabata K, Nakai H, Toda M. Kondo T, et al. Bioorg Med Chem. 2007 Apr 1;15(7):2631-50. doi: 10.1016/j.bmc.2007.01.041. Epub 2007 Jan 26. Bioorg Med Chem. 2007. PMID: 17293118

5

Discovery of long-acting N-(cyanomethyl)-N-alkyl-L-prolinamide inhibitors of dipeptidyl peptidase IV.

Kondo T, Nekado T, Sugimoto I, Ochi K, Takai S, Kinoshita A, Hatayama A, Yamamoto S, Kawabata K, Nakai H, Toda M. Kondo T, et al. Bioorg Med Chem. 2008 Jan 1;16(1):190-208. doi: 10.1016/j.bmc.2007.10.005. Epub 2007 Oct 5. Bioorg Med Chem. 2008. PMID: 17962025

6

6,7-Dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidines and their derivatives as novel corticotropin-releasing factor 1 receptor antagonists.

Saito T, Obitsu T, Kondo T, Matsui T, Nagao Y, Kusumi K, Matsumura N, Ueno S, Kishi A, Katsumata S, Kagamiishi Y, Nakai H, Toda M. Saito T, et al. Among authors: kondo t. Bioorg Med Chem. 2011 Sep 15;19(18):5432-45. doi: 10.1016/j.bmc.2011.07.055. Epub 2011 Jul 31. Bioorg Med Chem. 2011. PMID: 21865047

7

Highly potent inhibitors of TNF-alpha production. Part 1: Discovery of chemical leads.

Matsui T, Kondo T, Nishita Y, Itadani S, Nakatani S, Omawari N, Sakai M, Nakazawa S, Ogata A, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: kondo t. Bioorg Med Chem Lett. 2002 Mar 25;12(6):903-5. doi: 10.1016/s0960-894x(02)00036-7. Bioorg Med Chem Lett. 2002. PMID: 11958990

8

Highly potent inhibitors of TNF-alpha production. Part 2: identification of drug candidates.

Matsui T, Kondo T, Nishita Y, Itadani S, Tsuruta H, Fujita S, Omawari N, Sakai M, Nakazawa S, Ogata A, Mori H, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: kondo t. Bioorg Med Chem Lett. 2002 Mar 25;12(6):907-10. doi: 10.1016/s0960-894x(02)00037-9. Bioorg Med Chem Lett. 2002. PMID: 11958991

9

Highly potent inhibitors of TNF-alpha production. Part I: discovery of new chemical leads and their structure-activity relationships.

Matsui T, Kondo T, Nishita Y, Itadani S, Nakatani S, Omawari N, Sakai M, Nakazawa S, Ogata A, Mori H, Terai K, Kamoshima W, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: kondo t. Bioorg Med Chem. 2002 Dec;10(12):3757-86. doi: 10.1016/s0968-0896(02)00381-4. Bioorg Med Chem. 2002. PMID: 12413832

10

Highly potent inhibitors of TNF-alpha production. Part II: metabolic stabilization of a newly found chemical lead and conformational analysis of an active diastereoisomer.

Matsui T, Kondo T, Nishita Y, Itadani S, Tsuruta H, Fujita S, Omawari N, Sakai M, Nakazawa S, Ogata A, Mori H, Kamoshima W, Terai K, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: kondo t. Bioorg Med Chem. 2002 Dec;10(12):3787-805. doi: 10.1016/s0968-0896(02)00380-2. Bioorg Med Chem. 2002. PMID: 12413833

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