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PK/PD modeling links accelerated resolution of COVID-19-related clinical symptoms to SARS-CoV-2 viral load reduction in patients following treatment with Bamlanivimab alone or Bamlanivimab and Etesevimab together.
Ernest CS 2nd, Chien JY, Patel DR, Chigutsa E. Ernest CS 2nd, et al. Among authors: chigutsa e. CPT Pharmacometrics Syst Pharmacol. 2022 Jun;11(6):721-730. doi: 10.1002/psp4.12784. Epub 2022 Apr 5. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35289125 Free PMC article. Clinical Trial.
First-in-Human Study of Bamlanivimab in a Randomized Trial of Hospitalized Patients With COVID-19.
Chen P, Datta G, Grace Li Y, Chien J, Price K, Chigutsa E, Brown-Augsburger P, Poorbaugh J, Fill J, Benschop RJ, Rouphael N, Kay A, Mulligan MJ, Saxena A, Fischer WA, Dougan M, Klekotka P, Nirula A, Benson C. Chen P, et al. Among authors: chigutsa e. Clin Pharmacol Ther. 2021 Dec;110(6):1467-1477. doi: 10.1002/cpt.2405. Epub 2021 Oct 16. Clin Pharmacol Ther. 2021. PMID: 34455583 Free PMC article. Clinical Trial.
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