Johnston SRD - Search Results

1

Enhancing endocrine response with novel targeted therapies: why have the clinical trials to date failed to deliver on the preclinical promise?

Johnston SRD, Leary A, Martin LA, Smith IE, Dowsett M. Johnston SRD, et al. Cancer. 2008 Feb 1;112(3 Suppl):710-717. doi: 10.1002/cncr.23190. Cancer. 2008. PMID: 18072235 Free article.

2

Towards a molecular basis for tamoxifen resistance in breast cancer.

Johnston SR, Dowsett M, Smith IE. Johnston SR, et al. Ann Oncol. 1992 Jul;3(7):503-11. doi: 10.1093/oxfordjournals.annonc.a058251. Ann Oncol. 1992. PMID: 1498070 Free article. Review.

3

Changes in estrogen receptor, progesterone receptor, and pS2 expression in tamoxifen-resistant human breast cancer.

Johnston SR, Saccani-Jotti G, Smith IE, Salter J, Newby J, Coppen M, Ebbs SR, Dowsett M. Johnston SR, et al. Cancer Res. 1995 Aug 1;55(15):3331-8. Cancer Res. 1995. PMID: 7614468

4

Exon 5 deletion variant estrogen receptor messenger RNA expression in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer.

Daffada AA, Johnston SR, Smith IE, Detre S, King N, Dowsett M. Daffada AA, et al. Cancer Res. 1995 Jan 15;55(2):288-93. Cancer Res. 1995. PMID: 7812959

5

Modulation of Bcl-2 and Ki-67 expression in oestrogen receptor-positive human breast cancer by tamoxifen.

Johnston SR, MacLennan KA, Sacks NP, Salter J, Smith IE, Dowsett M. Johnston SR, et al. Eur J Cancer. 1994;30A(11):1663-9. doi: 10.1016/0959-8049(94)00327-2. Eur J Cancer. 1994. PMID: 7833141

6

Response to specific anti-oestrogen (ICI182780) in tamoxifen-resistant breast cancer.

Dowsett M, Johnston SR, Iveson TJ, Smith IE. Dowsett M, et al. Lancet. 1995 Feb 25;345(8948):525. doi: 10.1016/s0140-6736(95)90624-x. Lancet. 1995. PMID: 7861903 Clinical Trial. No abstract available.

7

Detection of wild type and exon 5-deleted splice variant oestrogen receptor (ER) mRNA in ER-positive and -negative breast cancer cell lines by reverse transcription/polymerase chain reaction.

Daffada AA, Johnston SR, Nicholls J, Dowsett M. Daffada AA, et al. J Mol Endocrinol. 1994 Dec;13(3):265-73. doi: 10.1677/jme.0.0130265. J Mol Endocrinol. 1994. PMID: 7893344

8

Acquired tamoxifen resistance in human breast cancer and reduced intra-tumoral drug concentration.

Johnston SR, Haynes BP, Smith IE, Jarman M, Sacks NP, Ebbs SR, Dowsett M. Johnston SR, et al. Lancet. 1993 Dec 18-25;342(8886-8887):1521-2. doi: 10.1016/s0140-6736(05)80088-1. Lancet. 1993. PMID: 7902904

9

Clinical and endocrine effects of the oral aromatase inhibitor vorozole in postmenopausal patients with advanced breast cancer.

Johnston SR, Smith IE, Doody D, Jacobs S, Robertshaw H, Dowsett M. Johnston SR, et al. Cancer Res. 1994 Nov 15;54(22):5875-81. Cancer Res. 1994. PMID: 7954417 Clinical Trial.

10

Comparison of new immunohistochemical assay for oestrogen receptor in paraffin wax embedded breast carcinoma tissue with quantitative enzyme immunoassay.

Saccani Jotti G, Johnston SR, Salter J, Detre S, Dowsett M. Saccani Jotti G, et al. J Clin Pathol. 1994 Oct;47(10):900-5. doi: 10.1136/jcp.47.10.900. J Clin Pathol. 1994. PMID: 7962603 Free PMC article.

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