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Type I collagen is thermally unstable at body temperature.
Leikina E, Mertts MV, Kuznetsova N, Leikin S. Leikina E, et al. Among authors: leikin s. Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1314-8. doi: 10.1073/pnas.032307099. Epub 2002 Jan 22. Proc Natl Acad Sci U S A. 2002. PMID: 11805290 Free PMC article.
Type I collagen triplet duplication mutation in lethal osteogenesis imperfecta shifts register of alpha chains throughout the helix and disrupts incorporation of mutant helices into fibrils and extracellular matrix.
Cabral WA, Mertts MV, Makareeva E, Colige A, Tekin M, Pandya A, Leikin S, Marini JC. Cabral WA, et al. Among authors: leikin s. J Biol Chem. 2003 Mar 21;278(12):10006-12. doi: 10.1074/jbc.M212523200. Epub 2003 Jan 20. J Biol Chem. 2003. PMID: 12538651 Free article.
236 results