Johnson AE - Search Results

1

Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions.

Soltani CE, Hotze EM, Johnson AE, Tweten RK. Soltani CE, et al. Among authors: johnson ae. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20226-31. doi: 10.1073/pnas.0708104105. Epub 2007 Dec 12. Proc Natl Acad Sci U S A. 2007. PMID: 18077338 Free PMC article.

2

Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin.

Hotze EM, Heuck AP, Czajkowsky DM, Shao Z, Johnson AE, Tweten RK. Hotze EM, et al. Among authors: johnson ae. J Biol Chem. 2002 Mar 29;277(13):11597-605. doi: 10.1074/jbc.M111039200. Epub 2002 Jan 17. J Biol Chem. 2002. PMID: 11799121 Free article.

3

Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins.

Giddings KS, Johnson AE, Tweten RK. Giddings KS, et al. Among authors: johnson ae. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11315-20. doi: 10.1073/pnas.2033520100. Epub 2003 Sep 19. Proc Natl Acad Sci U S A. 2003. PMID: 14500900 Free PMC article.

4

The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation.

Ramachandran R, Tweten RK, Johnson AE. Ramachandran R, et al. Among authors: johnson ae. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7139-44. doi: 10.1073/pnas.0500556102. Epub 2005 May 6. Proc Natl Acad Sci U S A. 2005. PMID: 15878993 Free PMC article.

5

Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin.

Soltani CE, Hotze EM, Johnson AE, Tweten RK. Soltani CE, et al. Among authors: johnson ae. J Biol Chem. 2007 May 25;282(21):15709-16. doi: 10.1074/jbc.M701173200. Epub 2007 Apr 5. J Biol Chem. 2007. PMID: 17412689 Free PMC article.

6

Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface.

Farrand AJ, LaChapelle S, Hotze EM, Johnson AE, Tweten RK. Farrand AJ, et al. Among authors: johnson ae. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4341-6. doi: 10.1073/pnas.0911581107. Epub 2010 Feb 9. Proc Natl Acad Sci U S A. 2010. PMID: 20145114 Free PMC article.

7

Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins.

Hotze EM, Wilson-Kubalek E, Farrand AJ, Bentsen L, Parker MW, Johnson AE, Tweten RK. Hotze EM, et al. Among authors: johnson ae. J Biol Chem. 2012 Jul 13;287(29):24534-43. doi: 10.1074/jbc.M112.380139. Epub 2012 May 29. J Biol Chem. 2012. PMID: 22645132 Free PMC article.

8

The Cholesterol-dependent Cytolysin Membrane-binding Interface Discriminates Lipid Environments of Cholesterol to Support β-Barrel Pore Insertion.

Farrand AJ, Hotze EM, Sato TK, Wade KR, Wimley WC, Johnson AE, Tweten RK. Farrand AJ, et al. Among authors: johnson ae. J Biol Chem. 2015 Jul 17;290(29):17733-17744. doi: 10.1074/jbc.M115.656769. Epub 2015 Jun 1. J Biol Chem. 2015. PMID: 26032415 Free PMC article.

9

The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins.

Shatursky O, Heuck AP, Shepard LA, Rossjohn J, Parker MW, Johnson AE, Tweten RK. Shatursky O, et al. Among authors: johnson ae. Cell. 1999 Oct 29;99(3):293-9. doi: 10.1016/s0092-8674(00)81660-8. Cell. 1999. PMID: 10555145 Free article.

10

The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins.

Shepard LA, Shatursky O, Johnson AE, Tweten RK. Shepard LA, et al. Among authors: johnson ae. Biochemistry. 2000 Aug 22;39(33):10284-93. doi: 10.1021/bi000436r. Biochemistry. 2000. PMID: 10956018

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