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Developing novel biopharmaceutical products through morphogenics.
Nicolaides NC, Sass PM, Chao Q, Kline JB, Ebel W, Routhier E, Zhou Y, Grasso L. Nicolaides NC, et al. Among authors: kline jb. Expert Opin Drug Discov. 2007 Dec;2(12):1619-29. doi: 10.1517/17460441.2.12.1619. Expert Opin Drug Discov. 2007. PMID: 23488905
The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity.
Lin J, Spidel JL, Maddage CJ, Rybinski KA, Kennedy RP, Krauthauser CL, Park YC, Albone EF, Jacob S, Goserud MT, Martinez BP, Chao Q, Zhou Y, Nicolaides NC, Kline JB, Grasso L. Lin J, et al. Among authors: kline jb. Cancer Biol Ther. 2013 Nov;14(11):1032-8. doi: 10.4161/cbt.26106. Epub 2013 Aug 28. Cancer Biol Ther. 2013. PMID: 24025360 Free PMC article.
Generation of therapeutic immunoconjugates via Residue-Specific Conjugation Technology (RESPECT) utilizing a native cysteine in the light chain framework of Oryctolagus cuniculus.
Albone EF, Spidel JL, Cheng X, Park YC, Jacob S, Milinichik AZ, Vaessen B, Butler J, Kline JB, Grasso L. Albone EF, et al. Among authors: kline jb. Cancer Biol Ther. 2017 May 4;18(5):347-357. doi: 10.1080/15384047.2017.1312232. Epub 2017 Apr 10. Cancer Biol Ther. 2017. PMID: 28394698 Free PMC article.
CA125 effects on humoral immunosuppression.
Kline JB, Nicolaides NC. Kline JB, et al. Aging (Albany NY). 2017 Oct 3;9(10):2010-2011. doi: 10.18632/aging.101301. Aging (Albany NY). 2017. PMID: 29016358 Free PMC article. No abstract available.
29 results