Hyde JE - Search Results

1

An atypical orthologue of 6-pyruvoyltetrahydropterin synthase can provide the missing link in the folate biosynthesis pathway of malaria parasites.

Dittrich S, Mitchell SL, Blagborough AM, Wang Q, Wang P, Sims PF, Hyde JE. Dittrich S, et al. Among authors: hyde je. Mol Microbiol. 2008 Feb;67(3):609-18. doi: 10.1111/j.1365-2958.2007.06073.x. Epub 2007 Dec 18. Mol Microbiol. 2008. PMID: 18093090 Free PMC article.

2

Transcriptional analysis of genes encoding enzymes of the folate pathway in the human malaria parasite Plasmodium falciparum.

Nirmalan N, Wang P, Sims PF, Hyde JE. Nirmalan N, et al. Among authors: hyde je. Mol Microbiol. 2002 Oct;46(1):179-90. doi: 10.1046/j.1365-2958.2002.03148.x. Mol Microbiol. 2002. PMID: 12366841 Free article.

3

Transfection studies to explore essential folate metabolism and antifolate drug synergy in the human malaria parasite Plasmodium falciparum.

Wang P, Wang Q, Aspinall TV, Sims PF, Hyde JE. Wang P, et al. Among authors: hyde je. Mol Microbiol. 2004 Mar;51(5):1425-38. doi: 10.1111/j.1365-2958.2003.03915.x. Mol Microbiol. 2004. PMID: 14982635 Free article.

4

Quantitative proteomics of the human malaria parasite Plasmodium falciparum and its application to studies of development and inhibition.

Nirmalan N, Sims PF, Hyde JE. Nirmalan N, et al. Among authors: hyde je. Mol Microbiol. 2004 May;52(4):1187-99. doi: 10.1111/j.1365-2958.2004.04049.x. Mol Microbiol. 2004. PMID: 15130134 Free article.

5

Genetic and metabolic analysis of folate salvage in the human malaria parasite Plasmodium falciparum.

Wang P, Nirmalan N, Wang Q, Sims PF, Hyde JE. Wang P, et al. Among authors: hyde je. Mol Biochem Parasitol. 2004 May;135(1):77-87. doi: 10.1016/j.molbiopara.2004.01.008. Mol Biochem Parasitol. 2004. PMID: 15287589

6

Characterisation of exogenous folate transport in Plasmodium falciparum.

Wang P, Wang Q, Sims PF, Hyde JE. Wang P, et al. Among authors: hyde je. Mol Biochem Parasitol. 2007 Jul;154(1):40-51. doi: 10.1016/j.molbiopara.2007.04.002. Epub 2007 Apr 8. Mol Biochem Parasitol. 2007. PMID: 17509698 Free PMC article.

7

Plasmodium falciparum: a paradigm for alternative folate biosynthesis in diverse microorganisms?

Hyde JE, Dittrich S, Wang P, Sims PF, de Crécy-Lagard V, Hanson AD. Hyde JE, et al. Trends Parasitol. 2008 Nov;24(11):502-8. doi: 10.1016/j.pt.2008.08.004. Epub 2008 Sep 19. Trends Parasitol. 2008. PMID: 18805734 Free PMC article.

8

Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition.

Wang P, Wang Q, Yang Y, Coward JK, Nzila A, Sims PF, Hyde JE. Wang P, et al. Among authors: hyde je. Mol Biochem Parasitol. 2010 Jul;172(1):41-51. doi: 10.1016/j.molbiopara.2010.03.012. Epub 2010 Mar 27. Mol Biochem Parasitol. 2010. PMID: 20350571 Free PMC article.

9

A protein-centric approach for the identification of folate enzymes from the malarial parasite, Plasmodium falciparum, using OFFGEL™ solution-based isoelectric focussing and mass spectrometry.

O'Cualain RD, Hyde JE, Sims PF. O'Cualain RD, et al. Among authors: hyde je. Malar J. 2010 Oct 18;9:286. doi: 10.1186/1475-2875-9-286. Malar J. 2010. PMID: 20955557 Free PMC article.

10

Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization.

Wang P, Read M, Sims PF, Hyde JE. Wang P, et al. Among authors: hyde je. Mol Microbiol. 1997 Mar;23(5):979-86. doi: 10.1046/j.1365-2958.1997.2821646.x. Mol Microbiol. 1997. PMID: 9076734 Free article.

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