Goodwin B - Search Results

1

The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor.

Wang H, Li H, Moore LB, Johnson MD, Maglich JM, Goodwin B, Ittoop OR, Wisely B, Creech K, Parks DJ, Collins JL, Willson TM, Kalpana GV, Venkatesh M, Xie W, Cho SY, Roboz J, Redinbo M, Moore JT, Mani S. Wang H, et al. Among authors: goodwin b. Mol Endocrinol. 2008 Apr;22(4):838-57. doi: 10.1210/me.2007-0218. Epub 2007 Dec 20. Mol Endocrinol. 2008. PMID: 18096694 Free PMC article.

2

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.

Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA. Maglich JM, et al. Among authors: goodwin b. Mol Pharmacol. 2002 Sep;62(3):638-46. doi: 10.1124/mol.62.3.638. Mol Pharmacol. 2002. PMID: 12181440

3

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.

Kliewer SA, Goodwin B, Willson TM. Kliewer SA, et al. Among authors: goodwin b. Endocr Rev. 2002 Oct;23(5):687-702. doi: 10.1210/er.2001-0038. Endocr Rev. 2002. PMID: 12372848 Review.

4

CAR: detailing new models.

Goodwin B, Moore JT. Goodwin B, et al. Trends Pharmacol Sci. 2004 Aug;25(8):437-41. doi: 10.1016/j.tips.2004.06.007. Trends Pharmacol Sci. 2004. PMID: 15276713 Review.

5

Regulation of cyp3a gene transcription by the pregnane x receptor.

Goodwin B, Redinbo MR, Kliewer SA. Goodwin B, et al. Annu Rev Pharmacol Toxicol. 2002;42:1-23. doi: 10.1146/annurev.pharmtox.42.111901.111051. Annu Rev Pharmacol Toxicol. 2002. PMID: 11807162 Review.

6

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.

Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT. Maglich JM, et al. Among authors: goodwin b. J Biol Chem. 2003 May 9;278(19):17277-83. doi: 10.1074/jbc.M300138200. Epub 2003 Feb 27. J Biol Chem. 2003. PMID: 12611900 Free article.

7

Nuclear receptor regulation of genes involved in bile acid metabolism.

Moore JT, Goodwin B, Willson TM, Kliewer SA. Moore JT, et al. Among authors: goodwin b. Crit Rev Eukaryot Gene Expr. 2002;12(2):119-35. doi: 10.1615/critreveukaryotgeneexpr.v12.i2.30. Crit Rev Eukaryot Gene Expr. 2002. PMID: 12434926 Review.

8

Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor.

Nallani SC, Goodwin B, Maglich JM, Buckley DJ, Buckley AR, Desai PB. Nallani SC, et al. Among authors: goodwin b. Drug Metab Dispos. 2003 May;31(5):681-4. doi: 10.1124/dmd.31.5.681. Drug Metab Dispos. 2003. PMID: 12695359

9

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.

Moore LB, Parks DJ, Jones SA, Bledsoe RK, Consler TG, Stimmel JB, Goodwin B, Liddle C, Blanchard SG, Willson TM, Collins JL, Kliewer SA. Moore LB, et al. Among authors: goodwin b. J Biol Chem. 2000 May 19;275(20):15122-7. doi: 10.1074/jbc.M001215200. J Biol Chem. 2000. PMID: 10748001 Free article.

10

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor.

Moore LB, Goodwin B, Jones SA, Wisely GB, Serabjit-Singh CJ, Willson TM, Collins JL, Kliewer SA. Moore LB, et al. Among authors: goodwin b. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7500-2. doi: 10.1073/pnas.130155097. Proc Natl Acad Sci U S A. 2000. PMID: 10852961 Free PMC article.

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