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The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor.
Wang H, Li H, Moore LB, Johnson MD, Maglich JM, Goodwin B, Ittoop OR, Wisely B, Creech K, Parks DJ, Collins JL, Willson TM, Kalpana GV, Venkatesh M, Xie W, Cho SY, Roboz J, Redinbo M, Moore JT, Mani S. Wang H, et al. Among authors: kalpana gv. Mol Endocrinol. 2008 Apr;22(4):838-57. doi: 10.1210/me.2007-0218. Epub 2007 Dec 20. Mol Endocrinol. 2008. PMID: 18096694 Free PMC article.
Rhabdoid tumor growth is inhibited by flavopiridol.
Smith ME, Cimica V, Chinni S, Challagulla K, Mani S, Kalpana GV. Smith ME, et al. Among authors: kalpana gv. Clin Cancer Res. 2008 Jan 15;14(2):523-32. doi: 10.1158/1078-0432.CCR-07-1347. Clin Cancer Res. 2008. PMID: 18223228
66 results