Xie W - Search Results

1

The antiapoptotic role of pregnane X receptor in human colon cancer cells.

Zhou J, Liu M, Zhai Y, Xie W. Zhou J, et al. Among authors: xie w. Mol Endocrinol. 2008 Apr;22(4):868-80. doi: 10.1210/me.2007-0197. Epub 2007 Dec 20. Mol Endocrinol. 2008. PMID: 18096695 Free PMC article.

2

Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.

Xie W, Yeuh MF, Radominska-Pandya A, Saini SP, Negishi Y, Bottroff BS, Cabrera GY, Tukey RH, Evans RM. Xie W, et al. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4150-5. doi: 10.1073/pnas.0438010100. Epub 2003 Mar 18. Proc Natl Acad Sci U S A. 2003. PMID: 12644700 Free PMC article.

3

Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor.

Rosenfeld JM, Vargas R Jr, Xie W, Evans RM. Rosenfeld JM, et al. Among authors: xie w. Mol Endocrinol. 2003 Jul;17(7):1268-82. doi: 10.1210/me.2002-0421. Epub 2003 Mar 27. Mol Endocrinol. 2003. PMID: 12663745

4

Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice.

Uppal H, Toma D, Saini SP, Ren S, Jones TJ, Xie W. Uppal H, et al. Among authors: xie w. Hepatology. 2005 Jan;41(1):168-76. doi: 10.1002/hep.20512. Hepatology. 2005. PMID: 15619241

5

Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice.

Saini SP, Mu Y, Gong H, Toma D, Uppal H, Ren S, Li S, Poloyac SM, Xie W. Saini SP, et al. Among authors: xie w. Hepatology. 2005 Mar;41(3):497-505. doi: 10.1002/hep.20570. Hepatology. 2005. PMID: 15726644

6

A pregnane X receptor agonist with unique species-dependent stereoselectivity and its implications in drug development.

Mu Y, Stephenson CR, Kendall C, Saini SP, Toma D, Ren S, Cai H, Strom SC, Day BW, Wipf P, Xie W. Mu Y, et al. Among authors: xie w. Mol Pharmacol. 2005 Aug;68(2):403-13. doi: 10.1124/mol.105.013292. Epub 2005 May 4. Mol Pharmacol. 2005. PMID: 15872116

7

Xenobiotic nuclear receptor-mediated regulation of UDP-glucuronosyl-transferases.

Zhou J, Zhang J, Xie W. Zhou J, et al. Among authors: xie w. Curr Drug Metab. 2005 Aug;6(4):289-98. doi: 10.2174/1389200054633853. Curr Drug Metab. 2005. PMID: 16101569 Review.

8

Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells.

Gong H, Singh SV, Singh SP, Mu Y, Lee JH, Saini SP, Toma D, Ren S, Kagan VE, Day BW, Zimniak P, Xie W. Gong H, et al. Among authors: xie w. Mol Endocrinol. 2006 Feb;20(2):279-90. doi: 10.1210/me.2005-0205. Epub 2005 Sep 29. Mol Endocrinol. 2006. PMID: 16195250

9

Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats.

Mu Y, Zhang J, Zhang S, Zhou HH, Toma D, Ren S, Huang L, Yaramus M, Baum A, Venkataramanan R, Xie W. Mu Y, et al. Among authors: xie w. J Pharmacol Exp Ther. 2006 Mar;316(3):1369-77. doi: 10.1124/jpet.105.094342. Epub 2005 Nov 2. J Pharmacol Exp Ther. 2006. PMID: 16267138

10

A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway.

Zhou J, Zhai Y, Mu Y, Gong H, Uppal H, Toma D, Ren S, Evans RM, Xie W. Zhou J, et al. Among authors: xie w. J Biol Chem. 2006 May 26;281(21):15013-20. doi: 10.1074/jbc.M511116200. Epub 2006 Mar 23. J Biol Chem. 2006. PMID: 16556603 Free PMC article.

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