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Page 1
Exploiting the molecular template of angiotensinogen in the discovery and design of peptidyl, pseudopeptidyl and peptidimimetic inhibitors of human renin: a structure-activity perspective.
Sawyer TK, Hester JB, Schostarez HJ, Thaisrivongs S, Bundy GL, Liu L, Bradford VS, De Vaux AE, Staples DJ, Maggiora LL, et al. Sawyer TK, et al. Among authors: hester jb. Adv Exp Med Biol. 1991;306:307-23. doi: 10.1007/978-1-4684-6012-4_37. Adv Exp Med Biol. 1991. PMID: 1812721 Review. No abstract available.
Design, structure-activity, and molecular modeling studies of potent renin inhibitory peptides having N-terminal Nin-For-Trp (Ftr): angiotensinogen congeners modified by P1-P1' Phe-Phe, Sta, Leu psi[CH(OH)CH2]Val or leu psi[CH2NH]Val substitutions.
Sawyer TK, Pals DT, Mao B, Staples DJ, de Vaux AE, Maggiora LL, Affholter JA, Kati W, Duchamp D, Hester JB, et al. Sawyer TK, et al. Among authors: hester jb. J Med Chem. 1988 Jan;31(1):18-30. doi: 10.1021/jm00396a006. J Med Chem. 1988. PMID: 3275777
HIV protease (HIV PR) inhibitor structure-activity-selectivity, and active site molecular modeling of high affinity Leu [CH(OH)CH2]Val modified viral and nonviral substrate analogs.
Sawyer TK, Staples DJ, Liu L, Tomasselli AG, Hui JO, O'Connell K, Schostarez H, Hester JB, Moon J, Howe WJ, et al. Sawyer TK, et al. Among authors: hester jb. Int J Pept Protein Res. 1992 Sep-Oct;40(3-4):274-81. doi: 10.1111/j.1399-3011.1992.tb00302.x. Int J Pept Protein Res. 1992. PMID: 1478785
Nitrogen-carbon-linked (azolylphenyl)oxazolidinones with potent antibacterial activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.
Genin MJ, Hutchinson DK, Allwine DA, Hester JB, Emmert DE, Garmon SA, Ford CW, Zurenko GE, Hamel JC, Schaadt RD, Stapert D, Yagi BH, Friis JM, Shobe EM, Adams WJ. Genin MJ, et al. Among authors: hester jb. J Med Chem. 1998 Dec 17;41(26):5144-7. doi: 10.1021/jm980546k. J Med Chem. 1998. PMID: 9857083 No abstract available.
Substituent effects on the antibacterial activity of nitrogen-carbon-linked (azolylphenyl)oxazolidinones with expanded activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.
Genin MJ, Allwine DA, Anderson DJ, Barbachyn MR, Emmert DE, Garmon SA, Graber DR, Grega KC, Hester JB, Hutchinson DK, Morris J, Reischer RJ, Ford CW, Zurenko GE, Hamel JC, Schaadt RD, Stapert D, Yagi BH. Genin MJ, et al. Among authors: hester jb. J Med Chem. 2000 Mar 9;43(5):953-70. doi: 10.1021/jm990373e. J Med Chem. 2000. PMID: 10715160
37 results