Tomasselli AG - Search Results

1

The evaluation of non-viral substrates of the HIV protease as leads in the design of inhibitors for AIDS therapy.

Tomasselli AG, Hui JO, Sawyer TK, Thaisrivongs S, Hester JB, Heinrikson RL. Tomasselli AG, et al. Adv Exp Med Biol. 1991;306:469-82. doi: 10.1007/978-1-4684-6012-4_60. Adv Exp Med Biol. 1991. PMID: 1812744

2

HIV protease (HIV PR) inhibitor structure-activity-selectivity, and active site molecular modeling of high affinity Leu [CH(OH)CH2]Val modified viral and nonviral substrate analogs.

Sawyer TK, Staples DJ, Liu L, Tomasselli AG, Hui JO, O'Connell K, Schostarez H, Hester JB, Moon J, Howe WJ, et al. Sawyer TK, et al. Among authors: tomasselli ag. Int J Pept Protein Res. 1992 Sep-Oct;40(3-4):274-81. doi: 10.1111/j.1399-3011.1992.tb00302.x. Int J Pept Protein Res. 1992. PMID: 1478785

3

Chemical synthesis of a biotinylated derivative of the simian immunodeficiency virus protease. Purification by avidin affinity chromatography and autocatalytic activation.

Tomasselli AG, Bannow CA, Deibel MR Jr, Hui JO, Zurcher-Neely HA, Reardon IM, Smith CW, Heinrikson RL. Tomasselli AG, et al. J Biol Chem. 1992 May 25;267(15):10232-7. J Biol Chem. 1992. PMID: 1587812 Free article.

4

A cumulative specificity model for proteases from human immunodeficiency virus types 1 and 2, inferred from statistical analysis of an extended substrate data base.

Poorman RA, Tomasselli AG, Heinrikson RL, Kézdy FJ. Poorman RA, et al. Among authors: tomasselli ag. J Biol Chem. 1991 Aug 5;266(22):14554-61. J Biol Chem. 1991. PMID: 1860861 Free article.

5

Inhibitors of the protease from human immunodeficiency virus: design and modeling of a compound containing a dihydroxyethylene isostere insert with high binding affinity and effective antiviral activity.

Thaisrivongs S, Tomasselli AG, Moon JB, Hui J, McQuade TJ, Turner SR, Strohbach JW, Howe WJ, Tarpley WG, Heinrikson RL. Thaisrivongs S, et al. Among authors: tomasselli ag. J Med Chem. 1991 Aug;34(8):2344-56. doi: 10.1021/jm00112a005. J Med Chem. 1991. PMID: 1875334

6

Zinc inhibition of renin and the protease from human immunodeficiency virus type 1.

Zhang ZY, Reardon IM, Hui JO, O'Connell KL, Poorman RA, Tomasselli AG, Heinrikson RL. Zhang ZY, et al. Among authors: tomasselli ag. Biochemistry. 1991 Sep 10;30(36):8717-21. doi: 10.1021/bi00100a001. Biochemistry. 1991. PMID: 1888732

7

Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.

Tomasselli AG, Hui JO, Adams L, Chosay J, Lowery D, Greenberg B, Yem A, Deibel MR, Zürcher-Neely H, Heinrikson RL. Tomasselli AG, et al. J Biol Chem. 1991 Aug 5;266(22):14548-53. J Biol Chem. 1991. PMID: 1907279 Free article.

8

Calcium-free calmodulin is a substrate of proteases from human immunodeficiency viruses 1 and 2.

Tomasselli AG, Howe WJ, Hui JO, Sawyer TK, Reardon IM, DeCamp DL, Craik CS, Heinrikson RL. Tomasselli AG, et al. Proteins. 1991;10(1):1-9. doi: 10.1002/prot.340100102. Proteins. 1991. PMID: 2062825

9

Interdomain hydrolysis of a truncated Pseudomonas exotoxin by the human immunodeficiency virus-1 protease.

Tomasselli AG, Hui JO, Sawyer TK, Staples DJ, FitzGerald DJ, Chaudhary VK, Pastan I, Heinrikson RL. Tomasselli AG, et al. J Biol Chem. 1990 Jan 5;265(1):408-13. J Biol Chem. 1990. PMID: 2104621 Free article.

10

Substrate analogue inhibition and active site titration of purified recombinant HIV-1 protease.

Tomasselli AG, Olsen MK, Hui JO, Staples DJ, Sawyer TK, Heinrikson RL, Tomich CS. Tomasselli AG, et al. Biochemistry. 1990 Jan 9;29(1):264-9. doi: 10.1021/bi00453a036. Biochemistry. 1990. PMID: 2182116

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