Brems DN - Search Results

1

Contributions of a disulfide bond to the structure, stability, and dimerization of human IgG1 antibody CH3 domain.

McAuley A, Jacob J, Kolvenbach CG, Westland K, Lee HJ, Brych SR, Rehder D, Kleemann GR, Brems DN, Matsumura M. McAuley A, et al. Among authors: brems dn. Protein Sci. 2008 Jan;17(1):95-106. doi: 10.1110/ps.073134408. Protein Sci. 2008. PMID: 18156469 Free PMC article.

2

Active dimer of Epratuzumab provides insight into the complex nature of an antibody aggregate.

Remmele RL Jr, Callahan WJ, Krishnan S, Zhou L, Bondarenko PV, Nichols AC, Kleemann GR, Pipes GD, Park S, Fodor S, Kras E, Brems DN. Remmele RL Jr, et al. Among authors: brems dn. J Pharm Sci. 2006 Jan;95(1):126-45. doi: 10.1002/jps.20515. J Pharm Sci. 2006. PMID: 16315222

3

Self-buffering antibody formulations.

Gokarn YR, Kras E, Nodgaard C, Dharmavaram V, Fesinmeyer RM, Hultgen H, Brych S, Remmele RL Jr, Brems DN, Hershenson S. Gokarn YR, et al. Among authors: brems dn. J Pharm Sci. 2008 Aug;97(8):3051-66. doi: 10.1002/jps.21232. J Pharm Sci. 2008. PMID: 18023013

4

Isomerization of a single aspartyl residue of anti-epidermal growth factor receptor immunoglobulin gamma2 antibody highlights the role avidity plays in antibody activity.

Rehder DS, Chelius D, McAuley A, Dillon TM, Xiao G, Crouse-Zeineddini J, Vardanyan L, Perico N, Mukku V, Brems DN, Matsumura M, Bondarenko PV. Rehder DS, et al. Among authors: brems dn. Biochemistry. 2008 Feb 26;47(8):2518-30. doi: 10.1021/bi7018223. Epub 2008 Jan 31. Biochemistry. 2008. PMID: 18232715

5

Assignment of 1H, 13C and 15N resonances of the reduced human IgG1 C(H)3 domain.

Liu D, Cocco M, Matsumura M, Ren D, Becker B, Remmele RL Jr, Brems DN. Liu D, et al. Among authors: brems dn. Biomol NMR Assign. 2007 Jul;1(1):93-4. doi: 10.1007/s12104-007-9026-z. Epub 2007 Jul 4. Biomol NMR Assign. 2007. PMID: 19636836

6

Denaturant-dependent conformational changes in a beta-trefoil protein: global and residue-specific aspects of an equilibrium denaturation process.

Latypov RF, Liu D, Jacob J, Harvey TS, Bondarenko PV, Kleemann GR, Brems DN, Raibekas AA. Latypov RF, et al. Among authors: brems dn. Biochemistry. 2009 Nov 24;48(46):10934-47. doi: 10.1021/bi901570k. Biochemistry. 2009. PMID: 19839644

7

Effect of ions on agitation- and temperature-induced aggregation reactions of antibodies.

Fesinmeyer RM, Hogan S, Saluja A, Brych SR, Kras E, Narhi LO, Brems DN, Gokarn YR. Fesinmeyer RM, et al. Among authors: brems dn. Pharm Res. 2009 Apr;26(4):903-13. doi: 10.1007/s11095-008-9792-z. Epub 2008 Dec 23. Pharm Res. 2009. PMID: 19104916

8

Structure and stability changes of human IgG1 Fc as a consequence of methionine oxidation.

Liu D, Ren D, Huang H, Dankberg J, Rosenfeld R, Cocco MJ, Li L, Brems DN, Remmele RL Jr. Liu D, et al. Among authors: brems dn. Biochemistry. 2008 May 6;47(18):5088-100. doi: 10.1021/bi702238b. Epub 2008 Apr 12. Biochemistry. 2008. PMID: 18407665

9

pH Dependence of structural stability of interleukin-2 and granulocyte colony-stimulating factor.

Ricci MS, Sarkar CA, Fallon EM, Lauffenburger DA, Brems DN. Ricci MS, et al. Among authors: brems dn. Protein Sci. 2003 May;12(5):1030-8. doi: 10.1110/ps.0230103. Protein Sci. 2003. PMID: 12717025 Free PMC article.

10

Aggregation of granulocyte-colony stimulating factor in vitro involves a conformationally altered monomeric state.

Raso SW, Abel J, Barnes JM, Maloney KM, Pipes G, Treuheit MJ, King J, Brems DN. Raso SW, et al. Among authors: brems dn. Protein Sci. 2005 Sep;14(9):2246-57. doi: 10.1110/ps.051489405. Protein Sci. 2005. PMID: 16131655 Free PMC article.

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