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High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome.
Kasprowicz V, Schulze Zur Wiesch J, Kuntzen T, Nolan BE, Longworth S, Berical A, Blum J, McMahon C, Reyor LL, Elias N, Kwok WW, McGovern BG, Freeman G, Chung RT, Klenerman P, Lewis-Ximenez L, Walker BD, Allen TM, Kim AY, Lauer GM. Kasprowicz V, et al. Among authors: chung rt. J Virol. 2008 Mar;82(6):3154-60. doi: 10.1128/JVI.02474-07. Epub 2007 Dec 26. J Virol. 2008. PMID: 18160439 Free PMC article.
The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1.
Kim AY, Lauer GM, Ouchi K, Addo MM, Lucas M, Schulze Zur Wiesch J, Timm J, Boczanowski M, Duncan JE, Wurcel AG, Casson D, Chung RT, Draenert R, Klenerman P, Walker BD. Kim AY, et al. Among authors: chung rt. Blood. 2005 Feb 1;105(3):1170-8. doi: 10.1182/blood-2004-06-2336. Epub 2004 Sep 30. Blood. 2005. PMID: 15459014 Free article.
CD8 epitope escape and reversion in acute HCV infection.
Timm J, Lauer GM, Kavanagh DG, Sheridan I, Kim AY, Lucas M, Pillay T, Ouchi K, Reyor LL, Schulze zur Wiesch J, Gandhi RT, Chung RT, Bhardwaj N, Klenerman P, Walker BD, Allen TM. Timm J, et al. Among authors: chung rt. J Exp Med. 2004 Dec 20;200(12):1593-604. doi: 10.1084/jem.20041006. J Exp Med. 2004. PMID: 15611288 Free PMC article.
Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes.
Schulze zur Wiesch J, Lauer GM, Day CL, Kim AY, Ouchi K, Duncan JE, Wurcel AG, Timm J, Jones AM, Mothe B, Allen TM, McGovern B, Lewis-Ximenez L, Sidney J, Sette A, Chung RT, Walker BD. Schulze zur Wiesch J, et al. Among authors: chung rt. J Immunol. 2005 Sep 15;175(6):3603-13. doi: 10.4049/jimmunol.175.6.3603. J Immunol. 2005. PMID: 16148104
687 results