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PARP1 proximity proteomics reveals interaction partners at stressed replication forks.
Mosler T, Baymaz HI, Gräf JF, Mikicic I, Blattner G, Bartlett E, Ostermaier M, Piccinno R, Yang J, Voigt A, Gatti M, Pellegrino S, Altmeyer M, Luck K, Ahel I, Roukos V, Beli P. Mosler T, et al. Among authors: ahel i. Nucleic Acids Res. 2022 Nov 11;50(20):11600-11618. doi: 10.1093/nar/gkac948. Nucleic Acids Res. 2022. PMID: 36350633 Free PMC article.
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 Macrodomain of SARS-CoV-2.
Gahbauer S, Correy GJ, Schuller M, Ferla MP, Doruk YU, Rachman M, Wu T, Diolaiti M, Wang S, Neitz RJ, Fearon D, Radchenko D, Moroz Y, Irwin JJ, Renslo AR, Taylor JC, Gestwicki JE, von Delft F, Ashworth A, Ahel I, Shoichet BK, Fraser JS. Gahbauer S, et al. Among authors: ahel i. bioRxiv [Preprint]. 2022 Jul 28:2022.06.27.497816. doi: 10.1101/2022.06.27.497816. bioRxiv. 2022. Update in: Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2212931120. doi: 10.1073/pnas.2212931120 PMID: 35794891 Free PMC article. Updated. Preprint.
Molecular basis for the reversible ADP-ribosylation of guanosine bases.
Schuller M, Raggiaschi R, Mikolcevic P, Rack JGM, Ariza A, Zhang Y, Ledermann R, Tang C, Mikoc A, Ahel I. Schuller M, et al. Among authors: ahel i. Mol Cell. 2023 Jul 6;83(13):2303-2315.e6. doi: 10.1016/j.molcel.2023.06.013. Epub 2023 Jun 29. Mol Cell. 2023. PMID: 37390817 Free PMC article.
Actions of aprataxin in multiple DNA repair pathways.
Rass U, Ahel I, West SC. Rass U, et al. Among authors: ahel i. J Biol Chem. 2007 Mar 30;282(13):9469-9474. doi: 10.1074/jbc.M611489200. Epub 2007 Feb 2. J Biol Chem. 2007. PMID: 17276982 Free article.
Defective DNA repair and neurodegenerative disease.
Rass U, Ahel I, West SC. Rass U, et al. Among authors: ahel i. Cell. 2007 Sep 21;130(6):991-1004. doi: 10.1016/j.cell.2007.08.043. Cell. 2007. PMID: 17889645 Free article. Review.
139 results