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MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting.
Pomella S, Cassandri M, D'Archivio L, Porrazzo A, Cossetti C, Phelps D, Perrone C, Pezzella M, Cardinale A, Wachtel M, Aloisi S, Milewski D, Colletti M, Sreenivas P, Walters ZS, Barillari G, Di Giannatale A, Milano GM, De Stefanis C, Alaggio R, Rodriguez-Rodriguez S, Carlesso N, Vakoc CR, Velardi E, Schafer BW, Guccione E, Gatz SA, Wasti A, Yohe M, Ignatius M, Quintarelli C, Shipley J, Miele L, Khan J, Houghton PJ, Marampon F, Gryder BE, De Angelis B, Locatelli F, Rota R. Pomella S, et al. Among authors: rota r. Nat Commun. 2023 Dec 15;14(1):8373. doi: 10.1038/s41467-023-44130-0. Nat Commun. 2023. PMID: 38102140 Free PMC article.
Translational Implications for Radiosensitizing Strategies in Rhabdomyosarcoma.
Pomella S, Porrazzo A, Cassandri M, Camero S, Codenotti S, Milazzo L, Vulcano F, Barillari G, Cenci G, Marchese C, Fanzani A, Megiorni F, Rota R, Marampon F. Pomella S, et al. Among authors: rota r. Int J Mol Sci. 2022 Oct 31;23(21):13281. doi: 10.3390/ijms232113281. Int J Mol Sci. 2022. PMID: 36362070 Free PMC article. Review.
Dual IGF1R/IR inhibitors in combination with GD2-CAR T-cells display a potent anti-tumor activity in diffuse midline glioma H3K27M-mutant.
de Billy E, Pellegrino M, Orlando D, Pericoli G, Ferretti R, Businaro P, Ajmone-Cat MA, Rossi S, Petrilli LL, Maestro N, Diomedi-Camassei F, Pezzullo M, De Stefanis C, Bencivenga P, Palma A, Rota R, Del Bufalo F, Massimi L, Weber G, Jones C, Carai A, Caruso S, De Angelis B, Caruana I, Quintarelli C, Mastronuzzi A, Locatelli F, Vinci M. de Billy E, et al. Among authors: rota r. Neuro Oncol. 2022 Jul 1;24(7):1150-1163. doi: 10.1093/neuonc/noab300. Neuro Oncol. 2022. PMID: 34964902 Free PMC article.
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS.
Ciarapica R, Carcarino E, Adesso L, De Salvo M, Bracaglia G, Leoncini PP, Dall'agnese A, Verginelli F, Milano GM, Boldrini R, Inserra A, Stifani S, Screpanti I, Marquez VE, Valente S, Mai A, Puri PL, Locatelli F, Palacios D, Rota R. Ciarapica R, et al. Among authors: rota r. BMC Cancer. 2014 Feb 27;14:139. doi: 10.1186/1471-2407-14-139. BMC Cancer. 2014. PMID: 24575771 Free PMC article.
Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells.
De Salvo M, Raimondi L, Vella S, Adesso L, Ciarapica R, Verginelli F, Pannuti A, Citti A, Boldrini R, Milano GM, Cacchione A, Ferrari A, Collini P, Rosolen A, Bisogno G, Alaggio R, Inserra A, Locatelli M, Stifani S, Screpanti I, Miele L, Locatelli F, Rota R. De Salvo M, et al. Among authors: rota r. PLoS One. 2014 May 5;9(5):e96238. doi: 10.1371/journal.pone.0096238. eCollection 2014. PLoS One. 2014. PMID: 24797362 Free PMC article.
Evaluation of Endoglin (CD105) expression in pediatric rhabdomyosarcoma.
Di Paolo V, Russo I, Boldrini R, Ravà L, Pezzullo M, Benedetti MC, Galardi A, Colletti M, Rota R, Orlando D, Crocoli A, Peinado H, Milano GM, Di Giannatale A. Di Paolo V, et al. Among authors: rota r. BMC Cancer. 2018 Jan 5;18(1):31. doi: 10.1186/s12885-017-3947-4. BMC Cancer. 2018. PMID: 29304781 Free PMC article.
The CRISP(Y) Future of Pediatric Soft Tissue Sarcomas.
Pomella S, Rota R. Pomella S, et al. Among authors: rota r. Front Chem. 2020 Mar 13;8:178. doi: 10.3389/fchem.2020.00178. eCollection 2020. Front Chem. 2020. PMID: 32232030 Free PMC article. Review.
134 results