Springael JY - Search Results

1

Highly potent HIV inhibition: engineering a key anti-HIV structure from PSC-RANTES into MIP-1 beta/CCL4.

Gaertner H, Lebeau O, Borlat I, Cerini F, Dufour B, Kuenzi G, Melotti A, Fish RJ, Offord R, Springael JY, Parmentier M, Hartley O. Gaertner H, et al. Among authors: springael jy. Protein Eng Des Sel. 2008 Feb;21(2):65-72. doi: 10.1093/protein/gzm079. Epub 2008 Jan 4. Protein Eng Des Sel. 2008. PMID: 18178567

2

Identification of nonpeptide CCR5 receptor agonists by structure-based virtual screening.

Kellenberger E, Springael JY, Parmentier M, Hachet-Haas M, Galzi JL, Rognan D. Kellenberger E, et al. Among authors: springael jy. J Med Chem. 2007 Mar 22;50(6):1294-303. doi: 10.1021/jm061389p. Epub 2007 Feb 21. J Med Chem. 2007. PMID: 17311371

3

Dimerization of chemokine receptors and its functional consequences.

Springael JY, Urizar E, Parmentier M. Springael JY, et al. Cytokine Growth Factor Rev. 2005 Dec;16(6):611-23. doi: 10.1016/j.cytogfr.2005.05.005. Epub 2005 Jun 23. Cytokine Growth Factor Rev. 2005. PMID: 15979374 Review.

4

The activation mechanism of chemokine receptor CCR5 involves common structural changes but a different network of interhelical interactions relative to rhodopsin.

Springael JY, de Poorter C, Deupi X, Van Durme J, Pardo L, Parmentier M. Springael JY, et al. Cell Signal. 2007 Jul;19(7):1446-56. doi: 10.1016/j.cellsig.2007.01.022. Epub 2007 Jan 25. Cell Signal. 2007. PMID: 17320349

5

Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers.

Sohy D, Parmentier M, Springael JY. Sohy D, et al. Among authors: springael jy. J Biol Chem. 2007 Oct 12;282(41):30062-9. doi: 10.1074/jbc.M705302200. Epub 2007 Aug 22. J Biol Chem. 2007. PMID: 17715128 Free article.

6

Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers.

El-Asmar L, Springael JY, Ballet S, Andrieu EU, Vassart G, Parmentier M. El-Asmar L, et al. Among authors: springael jy. Mol Pharmacol. 2005 Feb;67(2):460-9. doi: 10.1124/mol.104.003624. Epub 2004 Oct 27. Mol Pharmacol. 2005. PMID: 15509716

7

Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers.

Springael JY, Le Minh PN, Urizar E, Costagliola S, Vassart G, Parmentier M. Springael JY, et al. Mol Pharmacol. 2006 May;69(5):1652-61. doi: 10.1124/mol.105.019414. Epub 2006 Feb 7. Mol Pharmacol. 2006. PMID: 16467191

8

Consequences of ChemR23 heteromerization with the chemokine receptors CXCR4 and CCR7.

de Poorter C, Baertsoen K, Lannoy V, Parmentier M, Springael JY. de Poorter C, et al. Among authors: springael jy. PLoS One. 2013;8(2):e58075. doi: 10.1371/journal.pone.0058075. Epub 2013 Feb 28. PLoS One. 2013. PMID: 23469143 Free PMC article.

9

Partial Agonist and Biased Signaling Properties of the Synthetic Enantiomers J113863/UCB35625 at Chemokine Receptors CCR2 and CCR5.

Corbisier J, Huszagh A, Galés C, Parmentier M, Springael JY. Corbisier J, et al. Among authors: springael jy. J Biol Chem. 2017 Jan 13;292(2):575-584. doi: 10.1074/jbc.M116.757559. Epub 2016 Nov 28. J Biol Chem. 2017. PMID: 27895119 Free PMC article.

10

Allosteric properties of G protein-coupled receptor oligomers.

Springael JY, Urizar E, Costagliola S, Vassart G, Parmentier M. Springael JY, et al. Pharmacol Ther. 2007 Sep;115(3):410-8. doi: 10.1016/j.pharmthera.2007.06.004. Epub 2007 Jun 27. Pharmacol Ther. 2007. PMID: 17655934 Review.

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