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Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity.
Joseph A, Zheng JH, Follenzi A, Dilorenzo T, Sango K, Hyman J, Chen K, Piechocka-Trocha A, Brander C, Hooijberg E, Vignali DA, Walker BD, Goldstein H. Joseph A, et al. Among authors: sango k. J Virol. 2008 Mar;82(6):3078-89. doi: 10.1128/JVI.01812-07. Epub 2008 Jan 9. J Virol. 2008. PMID: 18184707 Free PMC article.
HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load.
Frahm N, Adams S, Kiepiela P, Linde CH, Hewitt HS, Lichterfeld M, Sango K, Brown NV, Pae E, Wurcel AG, Altfeld M, Feeney ME, Allen TM, Roach T, St John MA, Daar ES, Rosenberg E, Korber B, Marincola F, Walker BD, Goulder PJ, Brander C. Frahm N, et al. Among authors: sango k. J Virol. 2005 Aug;79(16):10218-25. doi: 10.1128/JVI.79.16.10218-10225.2005. J Virol. 2005. PMID: 16051815 Free PMC article.
Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities.
Frahm N, Korber BT, Adams CM, Szinger JJ, Draenert R, Addo MM, Feeney ME, Yusim K, Sango K, Brown NV, SenGupta D, Piechocka-Trocha A, Simonis T, Marincola FM, Wurcel AG, Stone DR, Russell CJ, Adolf P, Cohen D, Roach T, StJohn A, Khatri A, Davis K, Mullins J, Goulder PJ, Walker BD, Brander C. Frahm N, et al. Among authors: sango k. J Virol. 2004 Mar;78(5):2187-200. doi: 10.1128/jvi.78.5.2187-2200.2004. J Virol. 2004. PMID: 14963115 Free PMC article.
Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.
Frahm N, Kiepiela P, Adams S, Linde CH, Hewitt HS, Sango K, Feeney ME, Addo MM, Lichterfeld M, Lahaie MP, Pae E, Wurcel AG, Roach T, St John MA, Altfeld M, Marincola FM, Moore C, Mallal S, Carrington M, Heckerman D, Allen TM, Mullins JI, Korber BT, Goulder PJ, Walker BD, Brander C. Frahm N, et al. Among authors: sango k. Nat Immunol. 2006 Feb;7(2):173-8. doi: 10.1038/ni1281. Epub 2005 Dec 20. Nat Immunol. 2006. PMID: 16369537
Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses.
Bihl F, Frahm N, Di Giammarino L, Sidney J, John M, Yusim K, Woodberry T, Sango K, Hewitt HS, Henry L, Linde CH, Chisholm JV 3rd, Zaman TM, Pae E, Mallal S, Walker BD, Sette A, Korber BT, Heckerman D, Brander C. Bihl F, et al. Among authors: sango k. J Immunol. 2006 Apr 1;176(7):4094-101. doi: 10.4049/jimmunol.176.7.4094. J Immunol. 2006. PMID: 16547245
Extensive HLA class I allele promiscuity among viral CTL epitopes.
Frahm N, Yusim K, Suscovich TJ, Adams S, Sidney J, Hraber P, Hewitt HS, Linde CH, Kavanagh DG, Woodberry T, Henry LM, Faircloth K, Listgarten J, Kadie C, Jojic N, Sango K, Brown NV, Pae E, Zaman MT, Bihl F, Khatri A, John M, Mallal S, Marincola FM, Walker BD, Sette A, Heckerman D, Korber BT, Brander C. Frahm N, et al. Among authors: sango k. Eur J Immunol. 2007 Sep;37(9):2419-33. doi: 10.1002/eji.200737365. Eur J Immunol. 2007. PMID: 17705138 Free PMC article.
118 results