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Accessibility of a critical prion protein region involved in strain recognition and its implications for the early detection of prions.
Yuan J, Dong Z, Guo JP, McGeehan J, Xiao X, Wang J, Cali I, McGeer PL, Cashman NR, Bessen R, Surewicz WK, Kneale G, Petersen RB, Gambetti P, Zou WQ. Yuan J, et al. Among authors: mcgeehan j. Cell Mol Life Sci. 2008 Feb;65(4):631-43. doi: 10.1007/s00018-007-7478-z. Cell Mol Life Sci. 2008. PMID: 18193391 Free PMC article.
Concealment of epitope by reduction and alkylation in prion protein.
Yuan J, Kinter M, McGeehan J, Perry G, Kneale G, Gambetti P, Zou WQ. Yuan J, et al. Among authors: mcgeehan j. Biochem Biophys Res Commun. 2005 Jan 21;326(3):652-9. doi: 10.1016/j.bbrc.2004.11.088. Biochem Biophys Res Commun. 2005. PMID: 15596149
Failure to detect the presence of prions in the uterine and gestational tissues from a Gravida with Creutzfeldt-Jakob disease.
Xiao X, Miravalle L, Yuan J, McGeehan J, Dong Z, Wyza R, MacLennan GT, Golichowski AM, Kneale G, King N, Kong Q, Spina S, Vidal R, Ghetti B, Roos K, Gambetti P, Zou WQ. Xiao X, et al. Among authors: mcgeehan j. Am J Pathol. 2009 May;174(5):1602-8. doi: 10.2353/ajpath.2009.081045. Epub 2009 Apr 6. Am J Pathol. 2009. PMID: 19349373 Free PMC article.
PrP conformational transitions alter species preference of a PrP-specific antibody.
Zou WQ, Langeveld J, Xiao X, Chen S, McGeer PL, Yuan J, Payne MC, Kang HE, McGeehan J, Sy MS, Greenspan NS, Kaplan D, Wang GX, Parchi P, Hoover E, Kneale G, Telling G, Surewicz WK, Kong Q, Guo JP. Zou WQ, et al. Among authors: mcgeehan j. J Biol Chem. 2010 Apr 30;285(18):13874-84. doi: 10.1074/jbc.M109.088831. Epub 2010 Mar 1. J Biol Chem. 2010. PMID: 20194495 Free PMC article.
Amyloid-beta42 interacts mainly with insoluble prion protein in the Alzheimer brain.
Zou WQ, Xiao X, Yuan J, Puoti G, Fujioka H, Wang X, Richardson S, Zhou X, Zou R, Li S, Zhu X, McGeer PL, McGeehan J, Kneale G, Rincon-Limas DE, Fernandez-Funez P, Lee HG, Smith MA, Petersen RB, Guo JP. Zou WQ, et al. Among authors: mcgeehan j. J Biol Chem. 2011 Apr 29;286(17):15095-105. doi: 10.1074/jbc.M110.199356. Epub 2011 Mar 10. J Biol Chem. 2011. PMID: 21393248 Free PMC article.
91 results