Di Cristofano A - Search Results

1

Mammalian target of rapamycin is the key effector of phosphatidylinositol-3-OH-initiated proliferative signals in the thyroid follicular epithelium.

Yeager N, Brewer C, Cai KQ, Xu XX, Di Cristofano A. Yeager N, et al. Among authors: di cristofano a. Cancer Res. 2008 Jan 15;68(2):444-9. doi: 10.1158/0008-5472.CAN-07-3030. Cancer Res. 2008. PMID: 18199538

2

Pten loss in the mouse thyroid causes goiter and follicular adenomas: insights into thyroid function and Cowden disease pathogenesis.

Yeager N, Klein-Szanto A, Kimura S, Di Cristofano A. Yeager N, et al. Among authors: di cristofano a. Cancer Res. 2007 Feb 1;67(3):959-66. doi: 10.1158/0008-5472.CAN-06-3524. Cancer Res. 2007. PMID: 17283127

3

Thyroid-stimulating hormone initiated proliferative signals converge in vivo on the mTOR kinase without activating AKT.

Brewer C, Yeager N, Di Cristofano A. Brewer C, et al. Among authors: di cristofano a. Cancer Res. 2007 Sep 1;67(17):8002-6. doi: 10.1158/0008-5472.CAN-07-2471. Cancer Res. 2007. PMID: 17804710

4

Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo.

Miller KA, Yeager N, Baker K, Liao XH, Refetoff S, Di Cristofano A. Miller KA, et al. Among authors: di cristofano a. Cancer Res. 2009 Apr 15;69(8):3689-94. doi: 10.1158/0008-5472.CAN-09-0024. Epub 2009 Apr 7. Cancer Res. 2009. PMID: 19351816 Free PMC article.

5

Akt-mediated phosphorylation and activation of estrogen receptor alpha is required for endometrial neoplastic transformation in Pten+/- mice.

Vilgelm A, Lian Z, Wang H, Beauparlant SL, Klein-Szanto A, Ellenson LH, Di Cristofano A. Vilgelm A, et al. Among authors: di cristofano a. Cancer Res. 2006 Apr 1;66(7):3375-80. doi: 10.1158/0008-5472.CAN-05-4019. Cancer Res. 2006. PMID: 16585156

6

Activation of AKT kinases in cancer: implications for therapeutic targeting.

Bellacosa A, Kumar CC, Di Cristofano A, Testa JR. Bellacosa A, et al. Among authors: di cristofano a. Adv Cancer Res. 2005;94:29-86. doi: 10.1016/S0065-230X(05)94002-5. Adv Cancer Res. 2005. PMID: 16095999 Review.

7

GSK690693 delays tumor onset and progression in genetically defined mouse models expressing activated Akt.

Altomare DA, Zhang L, Deng J, Di Cristofano A, Klein-Szanto AJ, Kumar R, Testa JR. Altomare DA, et al. Among authors: di cristofano a. Clin Cancer Res. 2010 Jan 15;16(2):486-96. doi: 10.1158/1078-0432.CCR-09-1026. Clin Cancer Res. 2010. PMID: 20075391 Free PMC article.

8

A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice.

Tan Y, Timakhov RA, Rao M, Altomare DA, Xu J, Liu Z, Gao Q, Jhanwar SC, Di Cristofano A, Wiest DL, Knepper JE, Testa JR. Tan Y, et al. Among authors: di cristofano a. Cancer Res. 2008 Mar 1;68(5):1296-302. doi: 10.1158/0008-5472.CAN-07-3218. Cancer Res. 2008. PMID: 18316591

9

Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development.

Zeng Q, Phukan S, Xu Y, Sadim M, Rosman DS, Pennison M, Liao J, Yang GY, Huang CC, Valle L, Di Cristofano A, de la Chapelle A, Pasche B. Zeng Q, et al. Among authors: di cristofano a. Cancer Res. 2009 Jan 15;69(2):678-86. doi: 10.1158/0008-5472.CAN-08-3980. Cancer Res. 2009. PMID: 19147584 Free PMC article.

10

Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells.

Wang HQ, Altomare DA, Skele KL, Poulikakos PI, Kuhajda FP, Di Cristofano A, Testa JR. Wang HQ, et al. Among authors: di cristofano a. Oncogene. 2005 May 19;24(22):3574-82. doi: 10.1038/sj.onc.1208463. Oncogene. 2005. PMID: 15806173

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