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Phox2B mutations and the Delta-Notch pathway in neuroblastoma.
van Limpt V, Chan A, Schramm A, Eggert A, Versteeg R. van Limpt V, et al. Among authors: chan a. Cancer Lett. 2005 Oct 18;228(1-2):59-63. doi: 10.1016/j.canlet.2005.02.050. Cancer Lett. 2005. PMID: 16084642 Review.
The Phox2B homeobox gene is mutated in sporadic neuroblastomas.
van Limpt V, Schramm A, van Lakeman A, Sluis P, Chan A, van Noesel M, Baas F, Caron H, Eggert A, Versteeg R. van Limpt V, et al. Among authors: chan a. Oncogene. 2004 Dec 9;23(57):9280-8. doi: 10.1038/sj.onc.1208157. Oncogene. 2004. PMID: 15516980
Neuroblastoma is composed of two super-enhancer-associated differentiation states.
van Groningen T, Koster J, Valentijn LJ, Zwijnenburg DA, Akogul N, Hasselt NE, Broekmans M, Haneveld F, Nowakowska NE, Bras J, van Noesel CJM, Jongejan A, van Kampen AH, Koster L, Baas F, van Dijk-Kerkhoven L, Huizer-Smit M, Lecca MC, Chan A, Lakeman A, Molenaar P, Volckmann R, Westerhout EM, Hamdi M, van Sluis PG, Ebus ME, Molenaar JJ, Tytgat GA, Westerman BA, van Nes J, Versteeg R. van Groningen T, et al. Among authors: chan a. Nat Genet. 2017 Aug;49(8):1261-1266. doi: 10.1038/ng.3899. Epub 2017 Jun 26. Nat Genet. 2017. PMID: 28650485
A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma.
van Groningen T, Akogul N, Westerhout EM, Chan A, Hasselt NE, Zwijnenburg DA, Broekmans M, Stroeken P, Haneveld F, Hooijer GKJ, Savci-Heijink CD, Lakeman A, Volckmann R, van Sluis P, Valentijn LJ, Koster J, Versteeg R, van Nes J. van Groningen T, et al. Among authors: chan a. Nat Commun. 2019 Apr 4;10(1):1530. doi: 10.1038/s41467-019-09470-w. Nat Commun. 2019. PMID: 30948783 Free PMC article.
Mesenchymal-Type Neuroblastoma Cells Escape ALK Inhibitors.
Westerhout EM, Hamdi M, Stroeken P, Nowakowska NE, Lakeman A, van Arkel J, Hasselt NE, Bleijlevens B, Akogul N, Haneveld F, Chan A, van Sluis P, Zwijnenburg D, Volckmann R, van Noesel CJM, Adameyko I, van Groningen T, Koster J, Valentijn LJ, van Nes J, Versteeg R. Westerhout EM, et al. Among authors: chan a. Cancer Res. 2022 Feb 1;82(3):484-496. doi: 10.1158/0008-5472.CAN-21-1621. Epub 2021 Dec 1. Cancer Res. 2022. PMID: 34853072
9,427 results