Protter A - Search Results

1

Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension.

Zaiman AL, Podowski M, Medicherla S, Gordy K, Xu F, Zhen L, Shimoda LA, Neptune E, Higgins L, Murphy A, Chakravarty S, Protter A, Sehgal PB, Champion HC, Tuder RM. Zaiman AL, et al. Among authors: protter a. Am J Respir Crit Care Med. 2008 Apr 15;177(8):896-905. doi: 10.1164/rccm.200707-1083OC. Epub 2008 Jan 17. Am J Respir Crit Care Med. 2008. PMID: 18202349 Free PMC article.

2

Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor.

Bonniaud P, Margetts PJ, Kolb M, Schroeder JA, Kapoun AM, Damm D, Murphy A, Chakravarty S, Dugar S, Higgins L, Protter AA, Gauldie J. Bonniaud P, et al. Among authors: protter aa. Am J Respir Crit Care Med. 2005 Apr 15;171(8):889-98. doi: 10.1164/rccm.200405-612OC. Epub 2004 Nov 24. Am J Respir Crit Care Med. 2005. PMID: 15563636

3

Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model.

Tran TT, Uhl M, Ma JY, Janssen L, Sriram V, Aulwurm S, Kerr I, Lam A, Webb HK, Kapoun AM, Kizer DE, McEnroe G, Hart B, Axon J, Murphy A, Chakravarty S, Dugar S, Protter AA, Higgins LS, Wick W, Weller M, Wong DH. Tran TT, et al. Among authors: protter aa. Neuro Oncol. 2007 Jul;9(3):259-70. doi: 10.1215/15228517-2007-010. Epub 2007 May 23. Neuro Oncol. 2007. PMID: 17522330 Free PMC article.

4

Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression.

Kapoun AM, Gaspar NJ, Wang Y, Damm D, Liu YW, O'young G, Quon D, Lam A, Munson K, Tran TT, Ma JY, Murphy A, Dugar S, Chakravarty S, Protter AA, Wen FQ, Liu X, Rennard SI, Higgins LS. Kapoun AM, et al. Among authors: protter aa. Mol Pharmacol. 2006 Aug;70(2):518-31. doi: 10.1124/mol.105.021600. Epub 2006 May 17. Mol Pharmacol. 2006. PMID: 16707625

5

Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor-beta type I receptor kinase in vivo.

Ge R, Rajeev V, Ray P, Lattime E, Rittling S, Medicherla S, Protter A, Murphy A, Chakravarty J, Dugar S, Schreiner G, Barnard N, Reiss M. Ge R, et al. Among authors: protter a. Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4315-30. doi: 10.1158/1078-0432.CCR-06-0162. Clin Cancer Res. 2006. PMID: 16857807

6

Antitumor activity of TGF-beta inhibitor is dependent on the microenvironment.

Medicherla S, Li L, Ma JY, Kapoun AM, Gaspar NJ, Liu YW, Mangadu R, O'Young G, Protter AA, Schreiner GF, Wong DH, Higgins LS. Medicherla S, et al. Among authors: protter aa. Anticancer Res. 2007 Nov-Dec;27(6B):4149-57. Anticancer Res. 2007. PMID: 18229422 Free article.

7

Inhibition of p38 MAP kinase activity enhances axonal regeneration.

Myers RR, Sekiguchi Y, Kikuchi S, Scott B, Medicherla S, Protter A, Campana WM. Myers RR, et al. Among authors: protter a. Exp Neurol. 2003 Dec;184(2):606-14. doi: 10.1016/S0014-4886(03)00297-8. Exp Neurol. 2003. PMID: 14769353

8

A p38alpha selective mitogen-activated protein kinase inhibitor prevents periodontal bone loss.

Kirkwood KL, Li F, Rogers JE, Otremba J, Coatney DD, Kreider JM, D'Silva NJ, Chakravarty S, Dugar S, Higgins LS, Protter AA, Medicherla S. Kirkwood KL, et al. Among authors: protter aa. J Pharmacol Exp Ther. 2007 Jan;320(1):56-63. doi: 10.1124/jpet.106.112466. Epub 2006 Oct 13. J Pharmacol Exp Ther. 2007. PMID: 17041006

9

p38alpha-selective mitogen-activated protein kinase inhibitor SD-282 reduces inflammation in a subchronic model of tobacco smoke-induced airway inflammation.

Medicherla S, Fitzgerald MF, Spicer D, Woodman P, Ma JY, Kapoun AM, Chakravarty S, Dugar S, Protter AA, Higgins LS. Medicherla S, et al. Among authors: protter aa. J Pharmacol Exp Ther. 2008 Mar;324(3):921-9. doi: 10.1124/jpet.107.127092. Epub 2007 Dec 4. J Pharmacol Exp Ther. 2008. PMID: 18056868

10

Peripheral and central p38 MAPK mediates capsaicin-induced hyperalgesia.

Sweitzer SM, Peters MC, Ma JY, Kerr I, Mangadu R, Chakravarty S, Dugar S, Medicherla S, Protter AA, Yeomans DC. Sweitzer SM, et al. Among authors: protter aa. Pain. 2004 Oct;111(3):278-285. doi: 10.1016/j.pain.2004.07.007. Pain. 2004. PMID: 15363871

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