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Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo.
Brockschmidt C, Hirner H, Huber N, Eismann T, Hillenbrand A, Giamas G, Radunsky B, Ammerpohl O, Bohm B, Henne-Bruns D, Kalthoff H, Leithäuser F, Trauzold A, Knippschild U. Brockschmidt C, et al. Among authors: giamas g. Gut. 2008 Jun;57(6):799-806. doi: 10.1136/gut.2007.123695. Epub 2008 Jan 18. Gut. 2008. PMID: 18203806
Protein kinases as targets for cancer treatment.
Giamas G, Stebbing J, Vorgias CE, Knippschild U. Giamas G, et al. Pharmacogenomics. 2007 Aug;8(8):1005-16. doi: 10.2217/14622416.8.8.1005. Pharmacogenomics. 2007. PMID: 17716234 Review.
CK1delta modulates the transcriptional activity of ERalpha via AIB1 in an estrogen-dependent manner and regulates ERalpha-AIB1 interactions.
Giamas G, Castellano L, Feng Q, Knippschild U, Jacob J, Thomas RS, Coombes RC, Smith CL, Jiao LR, Stebbing J. Giamas G, et al. Nucleic Acids Res. 2009 May;37(9):3110-23. doi: 10.1093/nar/gkp136. Epub 2009 Apr 1. Nucleic Acids Res. 2009. Retraction in: Nucleic Acids Res. 2021 Nov 18;49(20):12006. doi: 10.1093/nar/gkab845 PMID: 19339517 Free PMC article. Retracted.
Kinases as targets in the treatment of solid tumors.
Giamas G, Man YL, Hirner H, Bischof J, Kramer K, Khan K, Ahmed SS, Stebbing J, Knippschild U. Giamas G, et al. Cell Signal. 2010 Jul;22(7):984-1002. doi: 10.1016/j.cellsig.2010.01.011. Epub 2010 Jan 21. Cell Signal. 2010. PMID: 20096351 Review.
Bendamustine as a model for the activity of alkylating agents.
Apostolopoulos C, Castellano L, Stebbing J, Giamas G. Apostolopoulos C, et al. Among authors: giamas g. Future Oncol. 2008 Jun;4(3):323-32. doi: 10.2217/14796694.4.3.323. Future Oncol. 2008. PMID: 18518757 Review.
102 results