Currie AJ - Search Results

1

Targeting the effector site with IFN-alphabeta-inducing TLR ligands reactivates tumor-resident CD8 T cell responses to eradicate established solid tumors.

Currie AJ, van der Most RG, Broomfield SA, Prosser AC, Tovey MG, Robinson BW. Currie AJ, et al. J Immunol. 2008 Feb 1;180(3):1535-44. doi: 10.4049/jimmunol.180.3.1535. J Immunol. 2008. PMID: 18209049

2

Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy.

van der Most RG, Currie AJ, Mahendran S, Prosser A, Darabi A, Robinson BW, Nowak AK, Lake RA. van der Most RG, et al. Among authors: currie aj. Cancer Immunol Immunother. 2009 Aug;58(8):1219-28. doi: 10.1007/s00262-008-0628-9. Epub 2008 Dec 4. Cancer Immunol Immunother. 2009. PMID: 19052741 Free PMC article.

3

Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapy.

Broomfield SA, van der Most RG, Prosser AC, Mahendran S, Tovey MG, Smyth MJ, Robinson BW, Currie AJ. Broomfield SA, et al. Among authors: currie aj. J Immunol. 2009 May 1;182(9):5217-24. doi: 10.4049/jimmunol.0803826. J Immunol. 2009. PMID: 19380767 Free article.

4

Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth.

van der Most RG, Currie AJ, Cleaver AL, Salmons J, Nowak AK, Mahendran S, Larma I, Prosser A, Robinson BW, Smyth MJ, Scalzo AA, Degli-Esposti MA, Lake RA. van der Most RG, et al. Among authors: currie aj. PLoS One. 2009 Sep 10;4(9):e6982. doi: 10.1371/journal.pone.0006982. PLoS One. 2009. PMID: 19746156 Free PMC article.

5

Dual control of antitumor CD8 T cells through the programmed death-1/programmed death-ligand 1 pathway and immunosuppressive CD4 T cells: regulation and counterregulation.

Currie AJ, Prosser A, McDonnell A, Cleaver AL, Robinson BW, Freeman GJ, van der Most RG. Currie AJ, et al. J Immunol. 2009 Dec 15;183(12):7898-908. doi: 10.4049/jimmunol.0901060. J Immunol. 2009. PMID: 20007574

6

CD8alpha+ DC are not the sole subset cross-presenting cell-associated tumor antigens from a solid tumor.

McDonnell AM, Prosser AC, van Bruggen I, Robinson BW, Currie AJ. McDonnell AM, et al. Among authors: currie aj. Eur J Immunol. 2010 Jun;40(6):1617-27. doi: 10.1002/eji.200940153. Eur J Immunol. 2010. PMID: 20373290 Free article.

7

Decoding dangerous death: how cytotoxic chemotherapy invokes inflammation, immunity or nothing at all.

van der Most RG, Currie AJ, Robinson BW, Lake RA. van der Most RG, et al. Among authors: currie aj. Cell Death Differ. 2008 Jan;15(1):13-20. doi: 10.1038/sj.cdd.4402255. Epub 2007 Nov 16. Cell Death Differ. 2008. PMID: 18007666 Review.

8

Partial, but not complete, tumor-debulking surgery promotes protective antitumor memory when combined with chemotherapy and adjuvant immunotherapy.

Broomfield S, Currie A, van der Most RG, Brown M, van Bruggen I, Robinson BW, Lake RA. Broomfield S, et al. Cancer Res. 2005 Sep 1;65(17):7580-4. doi: 10.1158/0008-5472.CAN-05-0328. Cancer Res. 2005. PMID: 16140921

9

Antitumor efficacy of the novel chemotherapeutic agent coramsine is potentiated by cotreatment with CpG-containing oligodeoxynucleotides.

van der Most RG, Himbeck R, Aarons S, Carter SJ, Larma I, Robinson C, Currie A, Lake RA. van der Most RG, et al. J Immunother. 2006 Mar-Apr;29(2):134-42. doi: 10.1097/01.cji.0000187958.38179.a9. J Immunother. 2006. PMID: 16531814

10

Intratumoral poly-N-acetyl glucosamine-based polymer matrix provokes a prolonged local inflammatory response that, when combined with IL-2, induces regression of malignant mesothelioma in a murine model.

van Bruggen I, Nelson DJ, Currie AJ, Jackaman C, Robinson BW. van Bruggen I, et al. Among authors: currie aj. J Immunother. 2005 Jul-Aug;28(4):359-67. doi: 10.1097/01.cji.0000170361.37832.ec. J Immunother. 2005. PMID: 16000954

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