Höhne M - Search Results

1

Efficient asymmetric synthesis of chiral amines by combining transaminase and pyruvate decarboxylase.

Höhne M, Kühl S, Robins K, Bornscheuer UT. Höhne M, et al. Chembiochem. 2008 Feb 15;9(3):363-5. doi: 10.1002/cbic.200700601. Chembiochem. 2008. PMID: 18213567 No abstract available.

2

Enzymatic removal of carboxyl protecting groups. 1. Cleavage of the tert-butyl moiety.

Schmidt M, Barbayianni E, Fotakopoulou I, Höhne M, Constantinou-Kokotou V, Bornscheuer UT, Kokotos G. Schmidt M, et al. Among authors: hohne m. J Org Chem. 2005 Apr 29;70(9):3737-40. doi: 10.1021/jo050114z. J Org Chem. 2005. PMID: 15845019

3

Rapid and sensitive kinetic assay for characterization of omega-transaminases.

Schätzle S, Höhne M, Redestad E, Robins K, Bornscheuer UT. Schätzle S, et al. Among authors: hohne m. Anal Chem. 2009 Oct 1;81(19):8244-8. doi: 10.1021/ac901640q. Anal Chem. 2009. PMID: 19739593

4

Conductometric method for the rapid characterization of the substrate specificity of amine-transaminases.

Schätzle S, Höhne M, Robins K, Bornscheuer UT. Schätzle S, et al. Among authors: hohne m. Anal Chem. 2010 Mar 1;82(5):2082-6. doi: 10.1021/ac9028483. Anal Chem. 2010. PMID: 20148590

5

Rational assignment of key motifs for function guides in silico enzyme identification.

Höhne M, Schätzle S, Jochens H, Robins K, Bornscheuer UT. Höhne M, et al. Nat Chem Biol. 2010 Nov;6(11):807-13. doi: 10.1038/nchembio.447. Epub 2010 Sep 26. Nat Chem Biol. 2010. PMID: 20871599

6

Crystallization and preliminary X-ray diffraction studies of the (R)-selective amine transaminase from Aspergillus fumigatus.

Thomsen M, Skalden L, Palm GJ, Höhne M, Bornscheuer UT, Hinrichs W. Thomsen M, et al. Among authors: hohne m. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Dec;69(Pt 12):1415-7. doi: 10.1107/S1744309113030923. Epub 2013 Nov 29. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 24316843 Free PMC article.

7

Protein engineering from "scratch" is maturing.

Höhne M, Bornscheuer UT. Höhne M, et al. Angew Chem Int Ed Engl. 2014 Jan 27;53(5):1200-2. doi: 10.1002/anie.201309591. Epub 2013 Dec 11. Angew Chem Int Ed Engl. 2014. PMID: 24339163

8

Crystallographic characterization of the (R)-selective amine transaminase from Aspergillus fumigatus.

Thomsen M, Skalden L, Palm GJ, Höhne M, Bornscheuer UT, Hinrichs W. Thomsen M, et al. Among authors: hohne m. Acta Crystallogr D Biol Crystallogr. 2014 Apr;70(Pt 4):1086-93. doi: 10.1107/S1399004714001084. Epub 2014 Mar 20. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24699652

9

Recent achievements in developing the biocatalytic toolbox for chiral amine synthesis.

Kohls H, Steffen-Munsberg F, Höhne M. Kohls H, et al. Among authors: hohne m. Curr Opin Chem Biol. 2014 Apr;19:180-92. doi: 10.1016/j.cbpa.2014.02.021. Epub 2014 Apr 12. Curr Opin Chem Biol. 2014. PMID: 24721252 Review.

10

Immobilization of (R)- and (S)-amine transaminases on chitosan support and their application for amine synthesis using isopropylamine as donor.

Mallin H, Höhne M, Bornscheuer UT. Mallin H, et al. Among authors: hohne m. J Biotechnol. 2014 Dec 10;191:32-7. doi: 10.1016/j.jbiotec.2014.05.015. Epub 2014 May 27. J Biotechnol. 2014. PMID: 24874095

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