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Page 1
A nonsteroidal glucocorticoid receptor antagonist.
Miner JN, Tyree C, Hu J, Berger E, Marschke K, Nakane M, Coghlan MJ, Clemm D, Lane B, Rosen J. Miner JN, et al. Among authors: marschke k. Mol Endocrinol. 2003 Jan;17(1):117-27. doi: 10.1210/me.2002-0010. Mol Endocrinol. 2003. PMID: 12511611
Antiinflammatory glucocorticoid receptor ligand with reduced side effects exhibits an altered protein-protein interaction profile.
Miner JN, Ardecky B, Benbatoul K, Griffiths K, Larson CJ, Mais DE, Marschke K, Rosen J, Vajda E, Zhi L, Negro-Vilar A. Miner JN, et al. Among authors: marschke k. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19244-9. doi: 10.1073/pnas.0705517104. Epub 2007 Nov 21. Proc Natl Acad Sci U S A. 2007. PMID: 18032610 Free PMC article.
Nuclear hormone receptor assays for drug discovery.
Rosen J, Marschke K, Rungta D. Rosen J, et al. Among authors: marschke k. Curr Opin Drug Discov Devel. 2003 Mar;6(2):224-30. Curr Opin Drug Discov Devel. 2003. PMID: 12669458 Review.
Biological characterization of a heterodimer-selective retinoid X receptor modulator: potential benefits for the treatment of type 2 diabetes.
Leibowitz MD, Ardecky RJ, Boehm MF, Broderick CL, Carfagna MA, Crombie DL, D'Arrigo J, Etgen GJ, Faul MM, Grese TA, Havel H, Hein NI, Heyman RA, Jolley D, Klausing K, Liu S, Mais DE, Mapes CM, Marschke KB, Michellys PY, Montrose-Rafizadeh C, Ogilvie KM, Pascual B, Rungta D, Tyhonas JS, Urcan MS, Wardlow M, Yumibe N, Reifel-Miller A. Leibowitz MD, et al. Among authors: marschke kb. Endocrinology. 2006 Feb;147(2):1044-53. doi: 10.1210/en.2005-0690. Epub 2005 Nov 3. Endocrinology. 2006. PMID: 16269450
5(Z)-benzylidene-1,2-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5H-1-aza-6-oxa-chrysenes as non-steroidal glucocorticoid receptor modulators.
Ardecky RJ, Hudson AR, Phillips DP, Tyhonas JS, Deckhut C, Lau TL, Li Y, Martinborough EA, Roach SL, Higuchi RI, Lopez FJ, Marschke KB, Miner JN, Karanewsky DS, Negro-Vilar A, Zhi L. Ardecky RJ, et al. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4158-62. doi: 10.1016/j.bmcl.2007.05.062. Epub 2007 May 23. Bioorg Med Chem Lett. 2007. PMID: 17553679
67 results