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Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism.
Le-Niculescu H, McFarland MJ, Ogden CA, Balaraman Y, Patel S, Tan J, Rodd ZA, Paulus M, Geyer MA, Edenberg HJ, Glatt SJ, Faraone SV, Nurnberger JI, Kuczenski R, Tsuang MT, Niculescu AB. Le-Niculescu H, et al. Am J Med Genet B Neuropsychiatr Genet. 2008 Mar 5;147B(2):134-66. doi: 10.1002/ajmg.b.30707. Am J Med Genet B Neuropsychiatr Genet. 2008. PMID: 18247375
Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms.
Le-Niculescu H, Patel SD, Bhat M, Kuczenski R, Faraone SV, Tsuang MT, McMahon FJ, Schork NJ, Nurnberger JI Jr, Niculescu AB 3rd. Le-Niculescu H, et al. Am J Med Genet B Neuropsychiatr Genet. 2009 Mar 5;150B(2):155-81. doi: 10.1002/ajmg.b.30887. Am J Med Genet B Neuropsychiatr Genet. 2009. PMID: 19025758
Evidence for genetic association of RORB with bipolar disorder.
McGrath CL, Glatt SJ, Sklar P, Le-Niculescu H, Kuczenski R, Doyle AE, Biederman J, Mick E, Faraone SV, Niculescu AB, Tsuang MT. McGrath CL, et al. BMC Psychiatry. 2009 Nov 12;9:70. doi: 10.1186/1471-244X-9-70. BMC Psychiatry. 2009. PMID: 19909500 Free PMC article.
Identification of blood biomarkers for psychosis using convergent functional genomics.
Kurian SM, Le-Niculescu H, Patel SD, Bertram D, Davis J, Dike C, Yehyawi N, Lysaker P, Dustin J, Caligiuri M, Lohr J, Lahiri DK, Nurnberger JI Jr, Faraone SV, Geyer MA, Tsuang MT, Schork NJ, Salomon DR, Niculescu AB. Kurian SM, et al. Mol Psychiatry. 2011 Jan;16(1):37-58. doi: 10.1038/mp.2009.117. Epub 2009 Nov 24. Mol Psychiatry. 2011. PMID: 19935739
40 results