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Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells.
Takada Y, Sethi G, Sung B, Aggarwal BB. Takada Y, et al. Among authors: sung b. Mol Pharmacol. 2008 May;73(5):1549-57. doi: 10.1124/mol.107.041350. Epub 2008 Feb 20. Mol Pharmacol. 2008. Retraction in: Mol Pharmacol. 2016 Jul;90(1):63. doi: 10.1124/mol.115.041350retraction PMID: 18287248 Retracted.
Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines.
Aggarwal BB, Banerjee S, Bharadwaj U, Sung B, Shishodia S, Sethi G. Aggarwal BB, et al. Among authors: sung b. Biochem Pharmacol. 2007 Apr 1;73(7):1024-32. doi: 10.1016/j.bcp.2006.12.010. Epub 2006 Dec 15. Biochem Pharmacol. 2007. Retraction in: Biochem Pharmacol. 2016 Feb 15;102:147. doi: 10.1016/j.bcp.2015.11.012 PMID: 17240359 Retracted.
Nuclear factor-kappaB activation: from bench to bedside.
Sethi G, Sung B, Aggarwal BB. Sethi G, et al. Among authors: sung b. Exp Biol Med (Maywood). 2008 Jan;233(1):21-31. doi: 10.3181/0707-MR-196. Exp Biol Med (Maywood). 2008. PMID: 18156302 Review.
Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis.
Sung B, Pandey MK, Ahn KS, Yi T, Chaturvedi MM, Liu M, Aggarwal BB. Sung B, et al. Blood. 2008 May 15;111(10):4880-91. doi: 10.1182/blood-2007-10-117994. Epub 2008 Mar 18. Blood. 2008. PMID: 18349320 Free PMC article.
564 results