Wartmann M - Search Results

1

Total synthesis of hypermodified epothilone analogs with potent in vitro antitumor activity.

Kuzniewski CN, Gertsch J, Wartmann M, Altmann KH. Kuzniewski CN, et al. Among authors: wartmann m. Org Lett. 2008 Mar 20;10(6):1183-6. doi: 10.1021/ol800089x. Epub 2008 Feb 28. Org Lett. 2008. PMID: 18303900

2

Total synthesis and biological assessment of benzimidazole-based analogues of epothilone A: ambivalent effects on cancer cell growth inhibition.

Cachoux F, Isarno T, Wartmann M, Altmann KH. Cachoux F, et al. Among authors: wartmann m. Chembiochem. 2006 Jan;7(1):54-7. doi: 10.1002/cbic.200500351. Chembiochem. 2006. PMID: 16345113 No abstract available.

3

Design and synthesis of 12-aza-epothilones (azathilones)--"non-natural" natural products with potent anticancer activity.

Feyen F, Gertsch J, Wartmann M, Altmann KH. Feyen F, et al. Among authors: wartmann m. Angew Chem Int Ed Engl. 2006 Sep 4;45(35):5880-5. doi: 10.1002/anie.200601359. Angew Chem Int Ed Engl. 2006. PMID: 16871640 No abstract available.

4

Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization.

Feyen F, Cachoux F, Gertsch J, Wartmann M, Altmann KH. Feyen F, et al. Among authors: wartmann m. Acc Chem Res. 2008 Jan;41(1):21-31. doi: 10.1021/ar700157x. Epub 2007 Dec 27. Acc Chem Res. 2008. PMID: 18159935 Review.

5

Natural products as leads for anticancer drug discovery: discovery of new chemotypes of microtubule stabilizers through reengineering of the epothilone scaffold.

Altmann KH, Cachoux F, Feyen F, Gertsch J, Kuzniewski CN, Wartmann M. Altmann KH, et al. Among authors: wartmann m. Chimia (Aarau). 2010;64(1-2):8-13. doi: 10.2533/chimia.2010.8. Chimia (Aarau). 2010. PMID: 21137676 Free article.

6

Patupilone (epothilone B, EPO906) inhibits growth and metastasis of experimental prostate tumors in vivo.

O'Reilly T, McSheehy PM, Wenger F, Hattenberger M, Muller M, Vaxelaire J, Altmann KH, Wartmann M. O'Reilly T, et al. Among authors: wartmann m. Prostate. 2005 Nov 1;65(3):231-40. doi: 10.1002/pros.20289. Prostate. 2005. PMID: 15948135

7

Scaffolds for microtubule inhibition through extensive modification of the epothilone template.

Cachoux F, Isarno T, Wartmann M, Altmann KH. Cachoux F, et al. Among authors: wartmann m. Angew Chem Int Ed Engl. 2005 Dec 1;44(45):7469-73. doi: 10.1002/anie.200501760. Angew Chem Int Ed Engl. 2005. PMID: 16240301 No abstract available.

8

Structure-activity relationships in side-chain-modified epothilone analogues--how important is the position of the nitrogen atom?

Bold G, Wojeik S, Caravatti G, Lindauer R, Stierlin C, Gertsch J, Wartmann M, Altmann KH. Bold G, et al. Among authors: wartmann m. ChemMedChem. 2006 Jan;1(1):37-40. doi: 10.1002/cmdc.200500051. ChemMedChem. 2006. PMID: 16892331 No abstract available.

9

Total synthesis and biological evaluation of a C(10)/C(12)-phenylene-bridged analog of epothilone D.

End N, Furet P, van Campenhout N, Wartmann M, Altmann KH. End N, et al. Among authors: wartmann m. Chem Biodivers. 2004 Nov;1(11):1771-84. doi: 10.1002/cbdv.200490133. Chem Biodivers. 2004. PMID: 17191815

10

Design, synthesis, and biological properties of highly potent epothilone B analogues.

Nicolaou KC, Sasmal PK, Rassias G, Reddy MV, Altmann KH, Wartmann M, O'Brate A, Giannakakou P. Nicolaou KC, et al. Among authors: wartmann m. Angew Chem Int Ed Engl. 2003 Aug 4;42(30):3515-20. doi: 10.1002/anie.200351819. Angew Chem Int Ed Engl. 2003. PMID: 12900969 No abstract available.

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