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An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.
Guzman ML, Rossi RM, Neelakantan S, Li X, Corbett CA, Hassane DC, Becker MW, Bennett JM, Sullivan E, Lachowicz JL, Vaughan A, Sweeney CJ, Matthews W, Carroll M, Liesveld JL, Crooks PA, Jordan CT. Guzman ML, et al. Among authors: corbett ca. Blood. 2007 Dec 15;110(13):4427-35. doi: 10.1182/blood-2007-05-090621. Epub 2007 Sep 5. Blood. 2007. PMID: 17804695 Free PMC article.
Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia.
Guzman ML, Yang N, Sharma KK, Balys M, Corbett CA, Jordan CT, Becker MW, Steidl U, Abdel-Wahab O, Levine RL, Marcucci G, Roboz GJ, Hassane DC. Guzman ML, et al. Among authors: corbett ca. Mol Cancer Ther. 2014 Aug;13(8):1979-90. doi: 10.1158/1535-7163.MCT-13-0963. Epub 2014 Jun 16. Mol Cancer Ther. 2014. PMID: 24934933 Free PMC article.
Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity.
Callahan KP, Minhajuddin M, Corbett C, Lagadinou ED, Rossi RM, Grose V, Balys MM, Pan L, Jacob S, Frontier A, Grever MR, Lucas DM, Kinghorn AD, Liesveld JL, Becker MW, Jordan CT. Callahan KP, et al. Among authors: corbett c. Leukemia. 2014 Oct;28(10):1960-8. doi: 10.1038/leu.2014.93. Epub 2014 Feb 28. Leukemia. 2014. PMID: 24577530 Free PMC article.
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.
Pei S, Minhajuddin M, Callahan KP, Balys M, Ashton JM, Neering SJ, Lagadinou ED, Corbett C, Ye H, Liesveld JL, O'Dwyer KM, Li Z, Shi L, Greninger P, Settleman J, Benes C, Hagen FK, Munger J, Crooks PA, Becker MW, Jordan CT. Pei S, et al. Among authors: corbett c. J Biol Chem. 2013 Nov 22;288(47):33542-33558. doi: 10.1074/jbc.M113.511170. Epub 2013 Oct 2. J Biol Chem. 2013. PMID: 24089526 Free PMC article. Clinical Trial.
OP-1 cDNA encodes an osteogenic protein in the TGF-beta family.
Ozkaynak E, Rueger DC, Drier EA, Corbett C, Ridge RJ, Sampath TK, Oppermann H. Ozkaynak E, et al. Among authors: corbett c. EMBO J. 1990 Jul;9(7):2085-93. doi: 10.1002/j.1460-2075.1990.tb07376.x. EMBO J. 1990. PMID: 2357959 Free PMC article.
602 results