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(3R,6S,7aS)-3-Phenyl-6-(phenyl-sulfan-yl)perhydro-pyrrolo[1,2-c]oxazol-5-one.
Gainsford GJ, Luxenburger A, Woolhouse AD. Gainsford GJ, et al. Among authors: woolhouse ad. Acta Crystallogr Sect E Struct Rep Online. 2009 Apr 2;65(Pt 5):o943. doi: 10.1107/S1600536809011623. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21583987 Free PMC article.
Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics.
Clinch K, Evans GB, Fröhlich RF, Gulab SA, Gutierrez JA, Mason JM, Schramm VL, Tyler PC, Woolhouse AD. Clinch K, et al. Among authors: woolhouse ad. Bioorg Med Chem. 2012 Sep 1;20(17):5181-7. doi: 10.1016/j.bmc.2012.07.006. Epub 2012 Jul 14. Bioorg Med Chem. 2012. PMID: 22854195 Free PMC article.
Synthesis of 12β-Methyl-18-nor-bile Acids.
Luxenburger A, Harris LD, Ure EM, Landaeta Aponte RA, Woolhouse AD, Cameron SA, Ling CD, Piltz RO, Lewis AR, Gainsford GJ, Weymouth-Wilson A, Furneaux RH. Luxenburger A, et al. Among authors: woolhouse ad. ACS Omega. 2021 Sep 14;6(38):25019-25039. doi: 10.1021/acsomega.1c04199. eCollection 2021 Sep 28. ACS Omega. 2021. PMID: 34604682 Free PMC article.
Synthesis and Characterization of Transition-State Analogue Inhibitors against Human DNA Methyltransferase 1.
Lamiable-Oulaidi F, Harijan RK, Shaffer KJ, Crump DR, Sun Y, Du Q, Gulab SA, Khan AA, Luxenburger A, Woolhouse AD, Sidoli S, Tyler PC, Schramm VL. Lamiable-Oulaidi F, et al. Among authors: woolhouse ad. J Med Chem. 2022 Apr 14;65(7):5462-5494. doi: 10.1021/acs.jmedchem.1c01869. Epub 2022 Mar 24. J Med Chem. 2022. PMID: 35324190 Free PMC article.
C5-Iminosugar modification of casein kinase 1δ lead 3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)isoxazole promotes enhanced inhibitor affinity and selectivity.
von Drathen T, Ure EM, Kirschner S, Roth A, Meier L, Woolhouse AD, Cameron SA, Knippschild U, Peifer C, Luxenburger A. von Drathen T, et al. Among authors: woolhouse ad. Arch Pharm (Weinheim). 2022 May;355(5):e2100497. doi: 10.1002/ardp.202100497. Epub 2022 Feb 17. Arch Pharm (Weinheim). 2022. PMID: 35174898
16 results