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Potent in vitro anti-Trypanosoma cruzi activity of pyridine-2-thiol N-oxide metal complexes having an inhibitory effect on parasite-specific fumarate reductase.
Vieites M, Smircich P, Parajón-Costa B, Rodríguez J, Galaz V, Olea-Azar C, Otero L, Aguirre G, Cerecetto H, González M, Gómez-Barrio A, Garat B, Gambino D. Vieites M, et al. Among authors: aguirre g. J Biol Inorg Chem. 2008 Jun;13(5):723-35. doi: 10.1007/s00775-008-0358-7. Epub 2008 Mar 6. J Biol Inorg Chem. 2008. PMID: 18322709
Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents.
Vieites M, Otero L, Santos D, Toloza J, Figueroa R, Norambuena E, Olea-Azar C, Aguirre G, Cerecetto H, González M, Morello A, Maya JD, Garat B, Gambino D. Vieites M, et al. Among authors: aguirre g. J Inorg Biochem. 2008 May-Jun;102(5-6):1033-43. doi: 10.1016/j.jinorgbio.2007.12.005. Epub 2007 Dec 23. J Inorg Biochem. 2008. PMID: 18226837
Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design.
Aguirre G, Cabrera E, Cerecetto H, Di Maio R, González M, Seoane G, Duffaut A, Denicola A, Gil MJ, Martínez-Merino V. Aguirre G, et al. Eur J Med Chem. 2004 May;39(5):421-31. doi: 10.1016/j.ejmech.2004.02.007. Eur J Med Chem. 2004. PMID: 15110968
616 results