Ludwig DL - Search Results

1

Generation and characterization of a therapeutic human antibody to melanoma antigen TYRP1.

Patel D, Balderes P, Lahiji A, Melchior M, Ng S, Bassi R, Wu Y, Griffith H, Jimenez X, Ludwig DL, Hicklin DJ, Kang X. Patel D, et al. Among authors: ludwig dl. Hum Antibodies. 2007;16(3-4):127-36. Hum Antibodies. 2007. PMID: 18334748

2

Conservation of receptor antagonist anti-tumor activity by epidermal growth factor receptor antibody expressed in transgenic corn seed.

Ludwig DL, Witte L, Hicklin DJ, Prewett M, Bassi R, Burtrum D, Pereira DS, Jimenez X, Fox F, Saxena B, Zhou Q, Ma Y, Kang X, Patel D, Barry M, Kussie P, Zhu Z, Russell DA, Petersen WL, Jury TP, Gaitan-Gaitan F, Moran DL, Delannay X, Storrs BS, Tou J, Zupec ME, Gustafson KS, McIntyre J, Tarnowski SJ, Bohlen P. Ludwig DL, et al. Hum Antibodies. 2004;13(3):81-90. Hum Antibodies. 2004. PMID: 15598988

3

Targeting the platelet-derived growth factor receptor alpha with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: implications as a potential therapeutic target.

Loizos N, Xu Y, Huber J, Liu M, Lu D, Finnerty B, Rolser R, Malikzay A, Persaud A, Corcoran E, Deevi DS, Balderes P, Bassi R, Jimenez X, Joynes CJ, Mangalampalli VR, Steiner P, Tonra JR, Wu Y, Pereira DS, Zhu Z, Ludwig DL, Hicklin DJ, Bohlen P, Witte L, Kussie P. Loizos N, et al. Among authors: ludwig dl. Mol Cancer Ther. 2005 Mar;4(3):369-79. doi: 10.1158/1535-7163.MCT-04-0114. Mol Cancer Ther. 2005. PMID: 15767546

4

IgG isotype, glycosylation, and EGFR expression determine the induction of antibody-dependent cellular cytotoxicity in vitro by cetuximab.

Patel D, Guo X, Ng S, Melchior M, Balderes P, Burtrum D, Persaud K, Luna X, Ludwig DL, Kang X. Patel D, et al. Among authors: ludwig dl. Hum Antibodies. 2010;19(4):89-99. doi: 10.3233/HAB-2010-0232. Hum Antibodies. 2010. PMID: 21178280

5

Monoclonal antibody therapeutics and apoptosis.

Ludwig DL, Pereira DS, Zhu Z, Hicklin DJ, Bohlen P. Ludwig DL, et al. Oncogene. 2003 Dec 8;22(56):9097-106. doi: 10.1038/sj.onc.1207104. Oncogene. 2003. PMID: 14663488 Review.

6

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

Burtrum D, Zhu Z, Lu D, Anderson DM, Prewett M, Pereira DS, Bassi R, Abdullah R, Hooper AT, Koo H, Jimenez X, Johnson D, Apblett R, Kussie P, Bohlen P, Witte L, Hicklin DJ, Ludwig DL. Burtrum D, et al. Among authors: ludwig dl. Cancer Res. 2003 Dec 15;63(24):8912-21. Cancer Res. 2003. PMID: 14695208

7

Suppression of leukemia expressing wild-type or ITD-mutant FLT3 receptor by a fully human anti-FLT3 neutralizing antibody.

Li Y, Li H, Wang MN, Lu D, Bassi R, Wu Y, Zhang H, Balderes P, Ludwig DL, Pytowski B, Kussie P, Piloto O, Small D, Bohlen P, Witte L, Zhu Z, Hicklin DJ. Li Y, et al. Among authors: ludwig dl. Blood. 2004 Aug 15;104(4):1137-44. doi: 10.1182/blood-2003-07-2585. Epub 2004 Apr 22. Blood. 2004. PMID: 15105287 Free article.

8

A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity.

Lu D, Zhang H, Koo H, Tonra J, Balderes P, Prewett M, Corcoran E, Mangalampalli V, Bassi R, Anselma D, Patel D, Kang X, Ludwig DL, Hicklin DJ, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: ludwig dl. J Biol Chem. 2005 May 20;280(20):19665-72. doi: 10.1074/jbc.M500815200. Epub 2005 Mar 9. J Biol Chem. 2005. PMID: 15757893 Free article.

9

Potent neutralization of VEGF biological activities with a fully human antibody Fab fragment directed against VEGF receptor 2.

Miao HQ, Hu K, Jimenez X, Navarro E, Zhang H, Lu D, Ludwig DL, Balderes P, Zhu Z. Miao HQ, et al. Among authors: ludwig dl. Biochem Biophys Res Commun. 2006 Jun 23;345(1):438-45. doi: 10.1016/j.bbrc.2006.04.119. Epub 2006 May 2. Biochem Biophys Res Commun. 2006. PMID: 16682007

10

Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member.

O'Toole JM, Rabenau KE, Burns K, Lu D, Mangalampalli V, Balderes P, Covino N, Bassi R, Prewett M, Gottfredsen KJ, Thobe MN, Cheng Y, Li Y, Hicklin DJ, Zhu Z, Waltz SE, Hayman MJ, Ludwig DL, Pereira DS. O'Toole JM, et al. Among authors: ludwig dl. Cancer Res. 2006 Sep 15;66(18):9162-70. doi: 10.1158/0008-5472.CAN-06-0283. Cancer Res. 2006. PMID: 16982759

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