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An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo.
Sinkevicius KW, Burdette JE, Woloszyn K, Hewitt SC, Hamilton K, Sugg SL, Temple KA, Wondisford FE, Korach KS, Woodruff TK, Greene GL. Sinkevicius KW, et al. Among authors: hewitt sc. Endocrinology. 2008 Jun;149(6):2970-9. doi: 10.1210/en.2007-1526. Epub 2008 Mar 13. Endocrinology. 2008. PMID: 18339713 Free PMC article.
Estrogen receptors: structure, mechanisms and function.
Hewitt SC, Korach KS. Hewitt SC, et al. Rev Endocr Metab Disord. 2002 Sep;3(3):193-200. doi: 10.1023/a:1020068224909. Rev Endocr Metab Disord. 2002. PMID: 12215714 Review. No abstract available.
70 results