Discovery of BBO-8520, a first-in-class direct and covalent dual inhibitor of GTP-bound (ON) and GDP-bound (OFF) KRASG12C.
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Maciag AE, et al. Among authors: sinkevicius kw.
Cancer Discov. 2024 Dec 6. doi: 10.1158/2159-8290.CD-24-0840. Online ahead of print.
Cancer Discov. 2024.
PMID: 39642212