Lahiri DK - Search Results

1

Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing.

Wen Y, Yu WH, Maloney B, Bailey J, Ma J, Marié I, Maurin T, Wang L, Figueroa H, Herman M, Krishnamurthy P, Liu L, Planel E, Lau LF, Lahiri DK, Duff K. Wen Y, et al. Among authors: lahiri dk. Neuron. 2008 Mar 13;57(5):680-90. doi: 10.1016/j.neuron.2008.02.024. Neuron. 2008. PMID: 18341989 Free PMC article.

2

BACE1 gene promoter is differentially regulated: detection of a novel promoter region for its cell type-specific regulation.

Lahiri DK, Maloney B, Ge YW. Lahiri DK, et al. J Mol Neurosci. 2006;28(2):193-210. doi: 10.1385/JMN:28:2:193. J Mol Neurosci. 2006. PMID: 16679558

3

Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells.

Lahiri DK, Maloney B, Ge YW. Lahiri DK, et al. J Mol Neurosci. 2006;29(1):65-80. doi: 10.1385/JMN:29:1:65. J Mol Neurosci. 2006. PMID: 16757811

4

Characterization of the human beta-secretase 2 (BACE2) 5'-flanking region: identification of a 268-bp region as the basal BACE2 promoter.

Maloney B, Ge YW, Greig NH, Lahiri DK. Maloney B, et al. Among authors: lahiri dk. J Mol Neurosci. 2006;29(1):81-99. doi: 10.1385/JMN:29:1:81. J Mol Neurosci. 2006. PMID: 16757812

5

Beyond the signaling effect role of amyloid-ß42 on the processing of APP, and its clinical implications.

Lahiri DK, Maloney B. Lahiri DK, et al. Exp Neurol. 2010 Sep;225(1):51-4. doi: 10.1016/j.expneurol.2010.04.018. Epub 2010 May 5. Exp Neurol. 2010. PMID: 20451519 Free PMC article. Review.

6

The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motif.

Maloney B, Lahiri DK. Maloney B, et al. Among authors: lahiri dk. Gene. 2011 Nov 15;488(1-2):1-12. doi: 10.1016/j.gene.2011.06.004. Epub 2011 Jun 15. Gene. 2011. PMID: 21699964 Free PMC article.

7

Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis.

Bailey JA, Maloney B, Ge YW, Lahiri DK. Bailey JA, et al. Among authors: lahiri dk. Gene. 2011 Nov 15;488(1-2):13-22. doi: 10.1016/j.gene.2011.06.017. Epub 2011 Jun 25. Gene. 2011. PMID: 21708232 Free PMC article.

8

Functional characterization of the 5' flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression.

Ge YW, Maloney B, Sambamurti K, Lahiri DK. Ge YW, et al. Among authors: lahiri dk. FASEB J. 2004 Jun;18(9):1037-9. doi: 10.1096/fj.03-1379fje. Epub 2004 Apr 1. FASEB J. 2004. PMID: 15059977

9

Neuronal differentiation is accompanied by increased levels of SNAP-25 protein in fetal rat primary cortical neurons: implications in neuronal plasticity and Alzheimer's disease.

Bailey JA, Lahiri DK. Bailey JA, et al. Among authors: lahiri dk. Ann N Y Acad Sci. 2006 Nov;1086:54-65. doi: 10.1196/annals.1377.001. Ann N Y Acad Sci. 2006. PMID: 17185505

10

Gene structure and organization of the human beta-secretase (BACE) promoter.

Sambamurti K, Kinsey R, Maloney B, Ge YW, Lahiri DK. Sambamurti K, et al. Among authors: lahiri dk. FASEB J. 2004 Jun;18(9):1034-6. doi: 10.1096/fj.03-1378fje. Epub 2004 Apr 1. FASEB J. 2004. PMID: 15059975

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