Pessoa-Mahana CD - Search Results

1

Computational modeling study of functional microdomains in cannabinoid receptor type 1.

Gonzalez A, Duran LS, Araya-Secchi R, Garate JA, Pessoa-Mahana CD, Lagos CF, Perez-Acle T. Gonzalez A, et al. Bioorg Med Chem. 2008 Apr 15;16(8):4378-89. doi: 10.1016/j.bmc.2008.02.070. Epub 2008 Feb 26. Bioorg Med Chem. 2008. PMID: 18342519

2

Design, synthesis, binding and docking-based 3D-QSAR studies of 2-pyridylbenzimidazoles--a new family of high affinity CB1 cannabinoid ligands.

Mella-Raipán JA, Lagos CF, Recabarren-Gajardo G, Espinosa-Bustos C, Romero-Parra J, Pessoa-Mahana H, Iturriaga-Vásquez P, Pessoa-Mahana CD. Mella-Raipán JA, et al. Molecules. 2013 Apr 4;18(4):3972-4001. doi: 10.3390/molecules18043972. Molecules. 2013. PMID: 23558540 Free PMC article.

3

Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor.

Pessoa-Mahana H, González-Lira C, Fierro A, Zapata-Torres G, Pessoa-Mahana CD, Ortiz-Severin J, Iturriaga-Vásquez P, Reyes-Parada M, Silva-Matus P, Saitz-Barría C, Araya-Maturana R. Pessoa-Mahana H, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7604-11. doi: 10.1016/j.bmc.2013.10.036. Epub 2013 Nov 6. Bioorg Med Chem. 2013. PMID: 24262884

4

Design, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1.

Espinosa-Bustos C, Lagos CF, Romero-Parra J, Zárate AM, Mella-Raipán J, Pessoa-Mahana H, Recabarren-Gajardo G, Iturriaga-Vásquez P, Tapia RA, Pessoa-Mahana CD. Espinosa-Bustos C, et al. Arch Pharm (Weinheim). 2015 Feb;348(2):81-8. doi: 10.1002/ardp.201400201. Epub 2015 Jan 13. Arch Pharm (Weinheim). 2015. PMID: 25641513

5

Extended N-Arylsulfonylindoles as 5-HT₆ Receptor Antagonists: Design, Synthesis & Biological Evaluation.

Vera G, Lagos CF, Almendras S, Hebel D, Flores F, Valle-Corvalán G, Pessoa-Mahana CD, Mella-Raipán J, Montecinos R, Recabarren-Gajardo G. Vera G, et al. Molecules. 2016 Aug 16;21(8):1070. doi: 10.3390/molecules21081070. Molecules. 2016. PMID: 27537868 Free PMC article.

6

Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.

Romero-Parra J, Mella-Raipán J, Palmieri V, Allarà M, Torres MJ, Pessoa-Mahana H, Iturriaga-Vásquez P, Escobar R, Faúndez M, Di Marzo V, Pessoa-Mahana CD. Romero-Parra J, et al. Eur J Med Chem. 2016 Nov 29;124:17-35. doi: 10.1016/j.ejmech.2016.08.005. Epub 2016 Aug 5. Eur J Med Chem. 2016. PMID: 27560280

7

2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human β₃-Adrenergic Activity.

Apablaza G, Montoya L, Morales-Verdejo C, Mellado M, Cuellar M, Lagos CF, Soto-Delgado J, Chung H, Pessoa-Mahana CD, Mella J. Apablaza G, et al. Among authors: pessoa mahana cd. Molecules. 2017 Mar 5;22(3):404. doi: 10.3390/molecules22030404. Molecules. 2017. PMID: 28273884 Free PMC article.

8

Cannabidiol binding and negative allosteric modulation at the cannabinoid type 1 receptor in the presence of delta-9-tetrahydrocannabinol: An In Silico study.

Chung H, Fierro A, Pessoa-Mahana CD. Chung H, et al. Among authors: pessoa mahana cd. PLoS One. 2019 Jul 23;14(7):e0220025. doi: 10.1371/journal.pone.0220025. eCollection 2019. PLoS One. 2019. PMID: 31335889 Free PMC article.

9

Motifs in Natural Products as Useful Scaffolds to Obtain Novel Benzo[d]imidazole-Based Cannabinoid Type 2 (CB2) Receptor Agonists.

Cho AYH, Chung H, Romero-Parra J, Kumar P, Allarà M, Ligresti A, Gallardo-Garrido C, Pessoa-Mahana H, Faúndez M, Pessoa-Mahana CD. Cho AYH, et al. Among authors: pessoa mahana cd. Int J Mol Sci. 2023 Jun 30;24(13):10918. doi: 10.3390/ijms241310918. Int J Mol Sci. 2023. PMID: 37446093 Free PMC article.

10

Synthesis, 5-hydroxytryptamine1A receptor affinity and docking studies of 3-[3-(4-aryl-1-piperazinyl)-propyl]-1H-indole derivatives.

Pessoa-Mahana H, Núñez CU, Araya-Maturana R, Barría CS, Zapata-Torres G, Pessoa-Mahana CD, Iturriaga-Vasquez P, Mella-Raipán J, Reyes-Parada M, Celis-Barros C. Pessoa-Mahana H, et al. Chem Pharm Bull (Tokyo). 2012;60(5):632-8. doi: 10.1248/cpb.60.632. Chem Pharm Bull (Tokyo). 2012. PMID: 22689401 Free article.

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