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Increase in thyroid follicular cell tumors in nelfinavir-treated rats observed in a 2-year carcinogenicity study is consistent with a rat-specific mechanism of thyroid neoplasia.
Burns-Naas LA, Zorbas M, Jessen B, Evering W, Stevens G, Ivett JL, Ryan TE, Cook JC, Capen CC, Chen M, Furman G, Theiss JC, Webber S, Wu E, Shetty B, Gasser R, McClain RM. Burns-Naas LA, et al. Among authors: evering w. Hum Exp Toxicol. 2005 Dec;24(12):643-54. doi: 10.1191/0960327105ht568oa. Hum Exp Toxicol. 2005. PMID: 16408618
Epithelial tissue hyperplasia induced by the RAF inhibitor PF-04880594 is attenuated by a clinically well-tolerated dose of the MEK inhibitor PD-0325901.
Torti VR, Wojciechowicz D, Hu W, John-Baptiste A, Evering W, Troche G, Marroquin LD, Smeal T, Yamazaki S, Palmer CL, Burns-Naas LA, Bagrodia S. Torti VR, et al. Among authors: evering w. Mol Cancer Ther. 2012 Oct;11(10):2274-83. doi: 10.1158/1535-7163.MCT-11-0984. Epub 2012 Jul 2. Mol Cancer Ther. 2012. PMID: 22752429
CDK4/6 Inhibition on Glucose and Pancreatic Beta Cell Homeostasis in Young and Aged Rats.
Sacaan AI, Thibault S, Hong M, Kondegowda NG, Nichols T, Li R, Rosselot C, Evering W, Fenutria R, Vitsky A, Brown T, Finkelstein M, Garcia-Ocaña A, Khan N, Stewart AF, Vasavada RC. Sacaan AI, et al. Among authors: evering w. Mol Cancer Res. 2017 Nov;15(11):1531-1541. doi: 10.1158/1541-7786.MCR-17-0172. Epub 2017 Jul 31. Mol Cancer Res. 2017. PMID: 28760782 Free article.
24 results