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Small-molecule inducers of insulin expression in pancreatic alpha-cells.
Fomina-Yadlin D, Kubicek S, Walpita D, Dancik V, Hecksher-Sørensen J, Bittker JA, Sharifnia T, Shamji A, Clemons PA, Wagner BK, Schreiber SL. Fomina-Yadlin D, et al. Among authors: wagner bk. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15099-104. doi: 10.1073/pnas.1010018107. Epub 2010 Aug 9. Proc Natl Acad Sci U S A. 2010. PMID: 20696901 Free PMC article.
Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells.
Kubicek S, Gilbert JC, Fomina-Yadlin D, Gitlin AD, Yuan Y, Wagner FF, Holson EB, Luo T, Lewis TA, Taylor B, Gupta S, Shamji AF, Wagner BK, Clemons PA, Schreiber SL. Kubicek S, et al. Among authors: wagner bk, wagner ff. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5364-9. doi: 10.1073/pnas.1201079109. Epub 2012 Mar 20. Proc Natl Acad Sci U S A. 2012. PMID: 22434908 Free PMC article.
Large-scale chemical dissection of mitochondrial function.
Wagner BK, Kitami T, Gilbert TJ, Peck D, Ramanathan A, Schreiber SL, Golub TR, Mootha VK. Wagner BK, et al. Nat Biotechnol. 2008 Mar;26(3):343-51. doi: 10.1038/nbt1387. Epub 2008 Feb 24. Nat Biotechnol. 2008. PMID: 18297058 Free PMC article.
A small-molecule inducer of PDX1 expression identified by high-throughput screening.
Yuan Y, Hartland K, Boskovic Z, Wang Y, Walpita D, Lysy PA, Zhong C, Young DW, Kim YK, Tolliday NJ, Sokal EM, Schreiber SL, Wagner BK. Yuan Y, et al. Among authors: wagner bk. Chem Biol. 2013 Dec 19;20(12):1513-22. doi: 10.1016/j.chembiol.2013.10.013. Epub 2013 Nov 27. Chem Biol. 2013. PMID: 24290880 Free PMC article.
136 results