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Determination of clinically relevant cutoffs for HIV-1 phenotypic resistance estimates through a combined analysis of clinical trial and cohort data.
Winters B, Montaner J, Harrigan PR, Gazzard B, Pozniak A, Miller MD, Emery S, van Leth F, Robinson P, Baxter JD, Perez-Elias M, Castor D, Hammer S, Rinehart A, Vermeiren H, Van Craenenbroeck E, Bacheler L. Winters B, et al. Among authors: van leth f, van craenenbroeck e. J Acquir Immune Defic Syndr. 2008 May 1;48(1):26-34. doi: 10.1097/QAI.0b013e31816d9bf4. J Acquir Immune Defic Syndr. 2008. PMID: 18360290
Cross-validated stepwise regression for identification of novel non-nucleoside reverse transcriptase inhibitor resistance associated mutations.
Van der Borght K, Van Craenenbroeck E, Lecocq P, Van Houtte M, Van Kerckhove B, Bacheler L, Verbeke G, van Vlijmen H. Van der Borght K, et al. Among authors: van craenenbroeck e, van houtte m, van kerckhove b, van vlijmen h. BMC Bioinformatics. 2011 Oct 3;12:386. doi: 10.1186/1471-2105-12-386. BMC Bioinformatics. 2011. PMID: 21966893 Free PMC article.
A comparative analysis of HIV drug resistance interpretation based on short reverse transcriptase sequences versus full sequences.
Steegen K, Bronze M, Van Craenenbroeck E, Winters B, Van der Borght K, Wallis CL, Stevens W, Rinke de Wit TF, Stuyver LJ; ART-A consortium. Steegen K, et al. Among authors: van craenenbroeck e, van der borght k. AIDS Res Ther. 2010 Oct 15;7:38. doi: 10.1186/1742-6405-7-38. AIDS Res Ther. 2010. PMID: 20950432 Free PMC article.
Advantages of predicted phenotypes and statistical learning models in inferring virological response to antiretroviral therapy from HIV genotype.
Altmann A, Sing T, Vermeiren H, Winters B, Van Craenenbroeck E, Van der Borght K, Rhee SY, Shafer RW, Schülter E, Kaiser R, Peres Y, Sönnerborg A, Fessel WJ, Incardona F, Zazzi M, Bacheler L, Van Vlijmen H, Lengauer T. Altmann A, et al. Among authors: van craenenbroeck e, van vlijmen h, van der borght k. Antivir Ther. 2009;14(2):273-83. Antivir Ther. 2009. PMID: 19430102
TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1.
Azijn H, Tirry I, Vingerhoets J, de Béthune MP, Kraus G, Boven K, Jochmans D, Van Craenenbroeck E, Picchio G, Rimsky LT. Azijn H, et al. Among authors: van craenenbroeck e. Antimicrob Agents Chemother. 2010 Feb;54(2):718-27. doi: 10.1128/AAC.00986-09. Epub 2009 Nov 23. Antimicrob Agents Chemother. 2010. PMID: 19933797 Free PMC article.
188 results