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HIV-1 p6 - a structured to flexible multifunctional membrane-interacting protein.
Solbak SM, Reksten TR, Hahn F, Wray V, Henklein P, Henklein P, Halskau Ø, Schubert U, Fossen T. Solbak SM, et al. Among authors: hahn f. Biochim Biophys Acta. 2013 Feb;1828(2):816-23. doi: 10.1016/j.bbamem.2012.11.010. Epub 2012 Nov 19. Biochim Biophys Acta. 2013. PMID: 23174350 Free article.
Proteolysis of mature HIV-1 p6 Gag protein by the insulin-degrading enzyme (IDE) regulates virus replication in an Env-dependent manner.
Hahn F, Schmalen A, Setz C, Friedrich M, Schlößer S, Kölle J, Spranger R, Rauch P, Fraedrich K, Reif T, Karius-Fischer J, Balasubramanyam A, Henklein P, Fossen T, Schubert U. Hahn F, et al. PLoS One. 2017 Apr 7;12(4):e0174254. doi: 10.1371/journal.pone.0174254. eCollection 2017. PLoS One. 2017. PMID: 28388673 Free PMC article. Clinical Trial.
Novel cytomegalovirus-inhibitory compounds of the class pyrrolopyridines show a complex pattern of target binding that suggests an unusual mechanism of antiviral activity.
Hahn F, Hutterer C, Henry C, Hamilton ST, Strojan H, Kraut A, Schulte U, Schütz M, Kohrt S, Wangen C, Pfizer J, Couté Y, Rawlinson WD, Strobl S, Marschall M. Hahn F, et al. Antiviral Res. 2018 Nov;159:84-94. doi: 10.1016/j.antiviral.2018.09.012. Epub 2018 Sep 27. Antiviral Res. 2018. PMID: 30268914
828 results