Kaspar BK - Search Results

1

Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity.

Dodge JC, Haidet AM, Yang W, Passini MA, Hester M, Clarke J, Roskelley EM, Treleaven CM, Rizo L, Martin H, Kim SH, Kaspar R, Taksir TV, Griffiths DA, Cheng SH, Shihabuddin LS, Kaspar BK. Dodge JC, et al. Among authors: kaspar bk, kaspar r. Mol Ther. 2008 Jun;16(6):1056-64. doi: 10.1038/mt.2008.60. Epub 2008 Apr 1. Mol Ther. 2008. PMID: 18388910 Free PMC article.

2

AAV as a gene transfer vector for the treatment of neurological disorders: novel treatment thoughts for ALS.

Hester ME, Foust KD, Kaspar RW, Kaspar BK. Hester ME, et al. Among authors: kaspar rw, kaspar bk. Curr Gene Ther. 2009 Oct;9(5):428-33. doi: 10.2174/156652309789753383. Curr Gene Ther. 2009. PMID: 19860657 Review.

3

AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice.

Dodge JC, Treleaven CM, Fidler JA, Hester M, Haidet A, Handy C, Rao M, Eagle A, Matthews JC, Taksir TV, Cheng SH, Shihabuddin LS, Kaspar BK. Dodge JC, et al. Among authors: kaspar bk. Mol Ther. 2010 Dec;18(12):2075-84. doi: 10.1038/mt.2010.206. Epub 2010 Sep 21. Mol Ther. 2010. PMID: 20859261 Free PMC article.

4

Disease progression in a mouse model of amyotrophic lateral sclerosis: the influence of chronic stress and corticosterone.

Fidler JA, Treleaven CM, Frakes A, Tamsett TJ, McCrate M, Cheng SH, Shihabuddin LS, Kaspar BK, Dodge JC. Fidler JA, et al. Among authors: kaspar bk. FASEB J. 2011 Dec;25(12):4369-77. doi: 10.1096/fj.11-190819. Epub 2011 Aug 29. FASEB J. 2011. PMID: 21876068 Free PMC article.

5

Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis.

Miller TM, Kim SH, Yamanaka K, Hester M, Umapathi P, Arnson H, Rizo L, Mendell JR, Gage FH, Cleveland DW, Kaspar BK. Miller TM, et al. Among authors: kaspar bk. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19546-51. doi: 10.1073/pnas.0609411103. Epub 2006 Dec 12. Proc Natl Acad Sci U S A. 2006. PMID: 17164329 Free PMC article.

6

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors.

Haidet AM, Rizo L, Handy C, Umapathi P, Eagle A, Shilling C, Boue D, Martin PT, Sahenk Z, Mendell JR, Kaspar BK. Haidet AM, et al. Among authors: kaspar bk. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4318-22. doi: 10.1073/pnas.0709144105. Epub 2008 Mar 11. Proc Natl Acad Sci U S A. 2008. PMID: 18334646 Free PMC article.

7

Could gene therapy be the future for muscular dystrophy?

Haidet AM, Mendell JR, Kaspar BK. Haidet AM, et al. Among authors: kaspar bk. Therapy. 2010 May 1;7(3):287-290. doi: 10.2217/thy.10.14. Therapy. 2010. PMID: 20543898 Free PMC article. No abstract available.

8

Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease.

Rodino-Klapac LR, Haidet AM, Kota J, Handy C, Kaspar BK, Mendell JR. Rodino-Klapac LR, et al. Among authors: kaspar bk. Muscle Nerve. 2009 Mar;39(3):283-96. doi: 10.1002/mus.21244. Muscle Nerve. 2009. PMID: 19208403 Free PMC article. Review.

9

Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes.

Hester ME, Murtha MJ, Song S, Rao M, Miranda CJ, Meyer K, Tian J, Boulting G, Schaffer DV, Zhu MX, Pfaff SL, Gage FH, Kaspar BK. Hester ME, et al. Among authors: kaspar bk. Mol Ther. 2011 Oct;19(10):1905-12. doi: 10.1038/mt.2011.135. Epub 2011 Jul 19. Mol Ther. 2011. PMID: 21772256 Free PMC article.

10

rAAV Gene Therapy in a Canavan's Disease Mouse Model Reveals Immune Impairments and an Extended Pathology Beyond the Central Nervous System.

Ahmed SS, Schattgen SA, Frakes AE, Sikoglu EM, Su Q, Li J, Hampton TG, Denninger AR, Kirschner DA, Kaspar B, Matalon R, Gao G. Ahmed SS, et al. Mol Ther. 2016 Jun;24(6):1030-1041. doi: 10.1038/mt.2016.68. Epub 2016 Apr 4. Mol Ther. 2016. PMID: 27039844 Free PMC article.

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