Concurrent and independent binding of Fcgamma receptors IIa and IIIb to surface-bound IgG.
Williams TE, Nagarajan S, Selvaraj P, Zhu C.
Williams TE, et al. Among authors: zhu c.
Biophys J. 2000 Oct;79(4):1867-75. doi: 10.1016/S0006-3495(00)76436-8.
Biophys J. 2000.
PMID: 11023892
Free PMC article.
CD16b bound human IgG with 2-3 times higher affinity than did CD32a (A(c)K(a) = 4.1 and 1.6 x 10(-7) microm(4), respectively) and both FcgammaRs had similar reverse kinetic rates (k(r) = 0.5 and 0.4 s(-1), respectively). ...The question of possible cross-regulation of bind …
CD16b bound human IgG with 2-3 times higher affinity than did CD32a (A(c)K(a) = 4.1 and 1.6 x 10(-7) microm(4), respectively) and bot …