Shafer WM - Search Results

1

Crystallization and preliminary X-ray diffraction analysis of the multidrug efflux transporter NorM from Neisseria gonorrhoeae.

Su CC, Long F, McDermott G, Shafer WM, Yu EW. Su CC, et al. Among authors: shafer wm. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Apr 1;64(Pt 4):289-92. doi: 10.1107/S1744309108006490. Epub 2008 Mar 21. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18391429 Free PMC article.

2

Characterization of the multiple transferable resistance repressor, MtrR, from Neisseria gonorrhoeae.

Hoffmann KM, Williams D, Shafer WM, Brennan RG. Hoffmann KM, et al. Among authors: shafer wm. J Bacteriol. 2005 Jul;187(14):5008-12. doi: 10.1128/JB.187.14.5008-5012.2005. J Bacteriol. 2005. PMID: 15995218 Free PMC article.

3

Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli.

Long F, Rouquette-Loughlin C, Shafer WM, Yu EW. Long F, et al. Among authors: shafer wm. Antimicrob Agents Chemother. 2008 Sep;52(9):3052-60. doi: 10.1128/AAC.00475-08. Epub 2008 Jun 30. Antimicrob Agents Chemother. 2008. PMID: 18591276 Free PMC article.

4

Efflux pumps of the resistance-nodulation-division family: a perspective of their structure, function, and regulation in gram-negative bacteria.

Routh MD, Zalucki Y, Su CC, Zhang Q, Shafer WM, Yu EW. Routh MD, et al. Among authors: shafer wm. Adv Enzymol Relat Areas Mol Biol. 2011;77:109-46. doi: 10.1002/9780470920541.ch3. Adv Enzymol Relat Areas Mol Biol. 2011. PMID: 21692368 Free PMC article. Review. No abstract available.

5

Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel.

Lei HT, Chou TH, Su CC, Bolla JR, Kumar N, Radhakrishnan A, Long F, Delmar JA, Do SV, Rajashankar KR, Shafer WM, Yu EW. Lei HT, et al. Among authors: shafer wm. PLoS One. 2014 Jun 5;9(6):e97475. doi: 10.1371/journal.pone.0097475. eCollection 2014. PLoS One. 2014. PMID: 24901251 Free PMC article.

6

Crystal structure of the Neisseria gonorrhoeae MtrD inner membrane multidrug efflux pump.

Bolla JR, Su CC, Do SV, Radhakrishnan A, Kumar N, Long F, Chou TH, Delmar JA, Lei HT, Rajashankar KR, Shafer WM, Yu EW. Bolla JR, et al. Among authors: shafer wm. PLoS One. 2014 Jun 5;9(6):e97903. doi: 10.1371/journal.pone.0097903. eCollection 2014. PLoS One. 2014. PMID: 24901477 Free PMC article.

7

Structure and function of Neisseria gonorrhoeae MtrF illuminates a class of antimetabolite efflux pumps.

Su CC, Bolla JR, Kumar N, Radhakrishnan A, Long F, Delmar JA, Chou TH, Rajashankar KR, Shafer WM, Yu EW. Su CC, et al. Among authors: shafer wm. Cell Rep. 2015 Apr 7;11(1):61-70. doi: 10.1016/j.celrep.2015.03.003. Epub 2015 Mar 26. Cell Rep. 2015. PMID: 25818299 Free PMC article.

8

Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance.

Lyu M, Moseng MA, Reimche JL, Holley CL, Dhulipala V, Su CC, Shafer WM, Yu EW. Lyu M, et al. Among authors: shafer wm. mBio. 2020 May 26;11(3):e00996-20. doi: 10.1128/mBio.00996-20. mBio. 2020. PMID: 32457251 Free PMC article.

9

Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump.

Lyu M, Ayala JC, Chirakos I, Su CC, Shafer WM, Yu EW. Lyu M, et al. Among authors: shafer wm. Microbiol Spectr. 2022 Oct 26;10(5):e0299022. doi: 10.1128/spectrum.02990-22. Epub 2022 Sep 19. Microbiol Spectr. 2022. PMID: 36121287 Free PMC article.

10

Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR.

Hooks GM, Ayala JC, Holley CL, Dhulipala V, Beggs GA, Perfect JR, Schumacher MA, Shafer WM, Brennan RG. Hooks GM, et al. Among authors: shafer wm. Nat Commun. 2024 Feb 7;15(1):1153. doi: 10.1038/s41467-024-45195-1. Nat Commun. 2024. PMID: 38326294 Free PMC article.

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