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Heparan sulfate accumulation with Abeta deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells.
O'Callaghan P, Sandwall E, Li JP, Yu H, Ravid R, Guan ZZ, van Kuppevelt TH, Nilsson LN, Ingelsson M, Hyman BT, Kalimo H, Lindahl U, Lannfelt L, Zhang X. O'Callaghan P, et al. Among authors: kalimo h. Brain Pathol. 2008 Oct;18(4):548-61. doi: 10.1111/j.1750-3639.2008.00152.x. Epub 2008 Apr 11. Brain Pathol. 2008. PMID: 18422760 Free PMC article.
The Arctic amyloid-β precursor protein (AβPP) mutation results in distinct plaques and accumulation of N- and C-truncated Aβ.
Philipson O, Lord A, Lalowski M, Soliymani R, Baumann M, Thyberg J, Bogdanovic N, Olofsson T, Tjernberg LO, Ingelsson M, Lannfelt L, Kalimo H, Nilsson LN. Philipson O, et al. Among authors: kalimo h. Neurobiol Aging. 2012 May;33(5):1010.e1-13. doi: 10.1016/j.neurobiolaging.2011.10.022. Epub 2011 Nov 26. Neurobiol Aging. 2012. PMID: 22118948
The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ.
Kalimo H, Lalowski M, Bogdanovic N, Philipson O, Bird TD, Nochlin D, Schellenberg GD, Brundin R, Olofsson T, Soliymani R, Baumann M, Wirths O, Bayer TA, Nilsson LN, Basun H, Lannfelt L, Ingelsson M. Kalimo H, et al. Acta Neuropathol Commun. 2013 Sep 10;1:60. doi: 10.1186/2051-5960-1-60. Acta Neuropathol Commun. 2013. PMID: 24252272 Free PMC article.
Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis.
Wirths O, Erck C, Martens H, Harmeier A, Geumann C, Jawhar S, Kumar S, Multhaup G, Walter J, Ingelsson M, Degerman-Gunnarsson M, Kalimo H, Huitinga I, Lannfelt L, Bayer TA. Wirths O, et al. Among authors: kalimo h. J Biol Chem. 2010 Dec 31;285(53):41517-24. doi: 10.1074/jbc.M110.178707. Epub 2010 Oct 22. J Biol Chem. 2010. PMID: 20971852 Free PMC article.
Monoclonal antibodies selective for α-synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and α-synuclein transgenic mice with the disease-causing A30P mutation.
Fagerqvist T, Lindström V, Nordström E, Lord A, Tucker SM, Su X, Sahlin C, Kasrayan A, Andersson J, Welander H, Näsström T, Holmquist M, Schell H, Kahle PJ, Kalimo H, Möller C, Gellerfors P, Lannfelt L, Bergström J, Ingelsson M. Fagerqvist T, et al. Among authors: kalimo h. J Neurochem. 2013 Jul;126(1):131-44. doi: 10.1111/jnc.12175. Epub 2013 Feb 27. J Neurochem. 2013. PMID: 23363402 Free article.
335 results