O'Callaghan P - Search Results

1

Heparan sulfate accumulation with Abeta deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells.

O'Callaghan P, Sandwall E, Li JP, Yu H, Ravid R, Guan ZZ, van Kuppevelt TH, Nilsson LN, Ingelsson M, Hyman BT, Kalimo H, Lindahl U, Lannfelt L, Zhang X. O'Callaghan P, et al. Brain Pathol. 2008 Oct;18(4):548-61. doi: 10.1111/j.1750-3639.2008.00152.x. Epub 2008 Apr 11. Brain Pathol. 2008. PMID: 18422760 Free PMC article.

2

Fe and C additions decrease the dissolution rate of silicon nitride coatings and are compatible with microglial viability in 3D collagen hydrogels.

Echeverri E, Skjöldebrand C, O'Callaghan P, Palmquist A, Kreuger J, Hulsart-Billström G, Persson C. Echeverri E, et al. Biomater Sci. 2023 May 2;11(9):3144-3158. doi: 10.1039/d2bm02074b. Biomater Sci. 2023. PMID: 36919682

3

Heparan sulfate mediates amyloid-beta internalization and cytotoxicity.

Sandwall E, O'Callaghan P, Zhang X, Lindahl U, Lannfelt L, Li JP. Sandwall E, et al. Glycobiology. 2010 May;20(5):533-41. doi: 10.1093/glycob/cwp205. Epub 2010 Jan 5. Glycobiology. 2010. PMID: 20053627

4

Animal models of amyloid-beta-related pathologies in Alzheimer's disease.

Philipson O, Lord A, Gumucio A, O'Callaghan P, Lannfelt L, Nilsson LN. Philipson O, et al. FEBS J. 2010 Mar;277(6):1389-409. doi: 10.1111/j.1742-4658.2010.07564.x. Epub 2010 Feb 3. FEBS J. 2010. PMID: 20136653 Free article. Review.

5

Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein.

Noborn F, O'Callaghan P, Hermansson E, Zhang X, Ancsin JB, Damas AM, Dacklin I, Presto J, Johansson J, Saraiva MJ, Lundgren E, Kisilevsky R, Westermark P, Li JP. Noborn F, et al. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5584-9. doi: 10.1073/pnas.1101194108. Epub 2011 Mar 21. Proc Natl Acad Sci U S A. 2011. PMID: 21422279 Free PMC article.

6

Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain.

Zhang X, Wang B, O'Callaghan P, Hjertström E, Jia J, Gong F, Zcharia E, Nilsson LN, Lannfelt L, Vlodavsky I, Lindahl U, Li JP. Zhang X, et al. Acta Neuropathol. 2012 Oct;124(4):465-78. doi: 10.1007/s00401-012-0997-1. Epub 2012 Jun 13. Acta Neuropathol. 2012. PMID: 22692572 Free PMC article.

7

Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways.

O'Callaghan P, Noborn F, Sehlin D, Li JP, Lannfelt L, Lindahl U, Zhang X. O'Callaghan P, et al. Amyloid. 2014 Jun;21(2):76-87. doi: 10.3109/13506129.2013.879643. Epub 2014 Feb 3. Amyloid. 2014. PMID: 24491019

8

Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response.

O'Callaghan P, Li JP, Lannfelt L, Lindahl U, Zhang X. O'Callaghan P, et al. J Biol Chem. 2015 Jun 12;290(24):14904-14. doi: 10.1074/jbc.M114.634337. Epub 2015 Apr 13. J Biol Chem. 2015. PMID: 25869127 Free PMC article.

9

Heparan Sulfate Proteoglycans as Relays of Neuroinflammation.

O'Callaghan P, Zhang X, Li JP. O'Callaghan P, et al. J Histochem Cytochem. 2018 Apr;66(4):305-319. doi: 10.1369/0022155417742147. Epub 2018 Jan 1. J Histochem Cytochem. 2018. PMID: 29290138 Free PMC article. Review.

10

Heparanase overexpression impedes perivascular clearance of amyloid-β from murine brain: relevance to Alzheimer's disease.

Zhang X, O'Callaghan P, Li H, Tan Y, Zhang G, Barash U, Wang X, Lannfelt L, Vlodavsky I, Lindahl U, Li JP. Zhang X, et al. Acta Neuropathol Commun. 2021 May 10;9(1):84. doi: 10.1186/s40478-021-01182-x. Acta Neuropathol Commun. 2021. PMID: 33971986 Free PMC article.

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