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Integration of in vivo and in vitro approaches to characterize the toxicity of Antalarmin, a corticotropin-releasing hormone receptor antagonist.
Horn TL, Harder JB, Johnson WD, Curry PT, Parchment RE, Morrissey RL, Mellick PW, Calis KA, Gold PW, Rice KC, Contoreggi C, Charney DS, Cizza G, Glaze ER, Tomaszewski JE, McCormick DL. Horn TL, et al. Among authors: contoreggi c. Toxicology. 2008 Jun 3;248(1):8-17. doi: 10.1016/j.tox.2008.03.002. Epub 2008 Mar 13. Toxicology. 2008. PMID: 18423834 Free PMC article.
Synthesis and biological activity of fluoro-substituted pyrrolo[2,3-d]pyrimidines: the development of potential positron emission tomography imaging agents for the corticotropin-releasing hormone type 1 receptor.
Hsin LW, Webster EL, Chrousos GP, Gold PW, Eckelman WC, Contoreggi C, Rice KC. Hsin LW, et al. Among authors: contoreggi c. Bioorg Med Chem Lett. 2000 Apr 17;10(8):707-10. doi: 10.1016/s0960-894x(00)00071-8. Bioorg Med Chem Lett. 2000. PMID: 10782669
Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates.
Habib KE, Weld KP, Rice KC, Pushkas J, Champoux M, Listwak S, Webster EL, Atkinson AJ, Schulkin J, Contoreggi C, Chrousos GP, McCann SM, Suomi SJ, Higley JD, Gold PW. Habib KE, et al. Among authors: contoreggi c. Proc Natl Acad Sci U S A. 2000 May 23;97(11):6079-84. doi: 10.1073/pnas.97.11.6079. Proc Natl Acad Sci U S A. 2000. PMID: 10823952 Free PMC article.
54 results