Kavanagh D - Search Results

1

A novel non-synonymous polymorphism (p.Arg240His) in C4b-binding protein is associated with atypical hemolytic uremic syndrome and leads to impaired alternative pathway cofactor activity.

Blom AM, Bergström F, Edey M, Diaz-Torres M, Kavanagh D, Lampe A, Goodship JA, Strain L, Moghal N, McHugh M, Inward C, Tomson C, Frémeaux-Bacchi V, Villoutreix BO, Goodship TH. Blom AM, et al. Among authors: kavanagh d. J Immunol. 2008 May 1;180(9):6385-91. doi: 10.4049/jimmunol.180.9.6385. J Immunol. 2008. PMID: 18424762

2

Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome.

Kavanagh D, Kemp EJ, Mayland E, Winney RJ, Duffield JS, Warwick G, Richards A, Ward R, Goodship JA, Goodship TH. Kavanagh D, et al. J Am Soc Nephrol. 2005 Jul;16(7):2150-5. doi: 10.1681/ASN.2005010103. Epub 2005 May 25. J Am Soc Nephrol. 2005. PMID: 15917334

3

Does complement factor B have a role in the pathogenesis of atypical HUS?

Kavanagh D, Kemp EJ, Richards A, Burgess RM, Mayland E, Goodship JA, Goodship TH. Kavanagh D, et al. Mol Immunol. 2006 Mar;43(7):856-9. doi: 10.1016/j.molimm.2005.06.041. Epub 2005 Aug 2. Mol Immunol. 2006. PMID: 16061287

4

Membrane cofactor protein and factor I: mutations and transplantation.

Kavanagh D, Goodship TH. Kavanagh D, et al. Semin Thromb Hemost. 2006 Mar;32(2):155-9. doi: 10.1055/s-2006-939771. Semin Thromb Hemost. 2006. PMID: 16575690 Review.

5

Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome.

Fremeaux-Bacchi V, Moulton EA, Kavanagh D, Dragon-Durey MA, Blouin J, Caudy A, Arzouk N, Cleper R, Francois M, Guest G, Pourrat J, Seligman R, Fridman WH, Loirat C, Atkinson JP. Fremeaux-Bacchi V, et al. Among authors: kavanagh d. J Am Soc Nephrol. 2006 Jul;17(7):2017-25. doi: 10.1681/ASN.2005101051. Epub 2006 Jun 8. J Am Soc Nephrol. 2006. PMID: 16762990

6

Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome.

Richards A, Kathryn Liszewski M, Kavanagh D, Fang CJ, Moulton E, Fremeaux-Bacchi V, Remuzzi G, Noris M, Goodship TH, Atkinson JP. Richards A, et al. Among authors: kavanagh d. Mol Immunol. 2007 Jan;44(1-3):111-22. doi: 10.1016/j.molimm.2006.07.004. Epub 2006 Aug 1. Mol Immunol. 2007. PMID: 16882452 Review.

7

Atypical haemolytic uraemic syndrome.

Kavanagh D, Goodship TH, Richards A. Kavanagh D, et al. Br Med Bull. 2006;77-78:5-22. doi: 10.1093/bmb/ldl004. Epub 2006 Sep 11. Br Med Bull. 2006. PMID: 16968692 Review.

8

Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome.

Kavanagh D, Richards A, Noris M, Hauhart R, Liszewski MK, Karpman D, Goodship JA, Fremeaux-Bacchi V, Remuzzi G, Goodship TH, Atkinson JP. Kavanagh D, et al. Mol Immunol. 2008 Jan;45(1):95-105. doi: 10.1016/j.molimm.2007.05.004. Epub 2007 Jun 26. Mol Immunol. 2008. PMID: 17597211

9

Screening for complement system abnormalities in patients with atypical hemolytic uremic syndrome.

Kavanagh D, Richards A, Fremeaux-Bacchi V, Noris M, Goodship T, Remuzzi G, Atkinson JP. Kavanagh D, et al. Clin J Am Soc Nephrol. 2007 May;2(3):591-6. doi: 10.2215/CJN.03270906. Epub 2007 Feb 14. Clin J Am Soc Nephrol. 2007. PMID: 17699467 Review. No abstract available.

10

Update on evaluating complement in hemolytic uremic syndrome.

Kavanagh D, Goodship TH. Kavanagh D, et al. Curr Opin Nephrol Hypertens. 2007 Nov;16(6):565-71. doi: 10.1097/MNH.0b013e3282f0872f. Curr Opin Nephrol Hypertens. 2007. PMID: 18089972 Review.

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