Mulato A - Search Results

1

Activation of 9-[(R)-2-[[(S)-[[(S)-1-(Isopropoxycarbonyl)ethyl]amino] phenoxyphosphinyl]-methoxy]propyl]adenine (GS-7340) and other tenofovir phosphonoamidate prodrugs by human proteases.

Birkus G, Kutty N, He GX, Mulato A, Lee W, McDermott M, Cihlar T. Birkus G, et al. Among authors: mulato a. Mol Pharmacol. 2008 Jul;74(1):92-100. doi: 10.1124/mol.108.045526. Epub 2008 Apr 22. Mol Pharmacol. 2008. PMID: 18430788

2

Novel mutation (K70E) in human immunodeficiency virus type 1 reverse transcriptase confers decreased susceptibility to 9-[2-(phosphonomethoxy)ethyl]adenine in vitro.

Cherrington JM, Mulato AS, Fuller MD, Chen MS. Cherrington JM, et al. Among authors: mulato as. Antimicrob Agents Chemother. 1996 Sep;40(9):2212-6. doi: 10.1128/AAC.40.9.2212. Antimicrob Agents Chemother. 1996. PMID: 8878611 Free PMC article.

3

In vitro characterization of the anti-human cytomegalovirus activity of PMEA (Adefovir).

Xiong X, Flores C, Fuller MD, Mendel DB, Mulato AS, Moon K, Chen MS, Cherrington JM. Xiong X, et al. Among authors: mulato as. Antiviral Res. 1997 Nov;36(2):131-7. doi: 10.1016/s0166-3542(97)00050-8. Antiviral Res. 1997. PMID: 9443670

4

Human immunodeficiency virus type 1 reverse transcriptase expressing the K70E mutation exhibits a decrease in specific activity and processivity.

Miller MD, Lamy PD, Fuller MD, Mulato AS, Margot NA, Cihlar T, Cherrington JM. Miller MD, et al. Among authors: mulato as. Mol Pharmacol. 1998 Aug;54(2):291-7. doi: 10.1124/mol.54.2.291. Mol Pharmacol. 1998. PMID: 9687570

5

A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture.

Cihlar T, Fuller MD, Mulato AS, Cherrington JM. Cihlar T, et al. Among authors: mulato as. Virology. 1998 Sep 1;248(2):382-93. doi: 10.1006/viro.1998.9299. Virology. 1998. PMID: 9721246 Free article.

6

Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.

Mulato AS, Ho ES, Cihlar T. Mulato AS, et al. J Pharmacol Exp Ther. 2000 Oct;295(1):10-5. J Pharmacol Exp Ther. 2000. PMID: 10991954

7

Adefovir and tenofovir susceptibilities of HIV-1 after 24 to 48 weeks of adefovir dipivoxil therapy: genotypic and phenotypic analyses of study GS-96-408.

Miller MD, Margot NA, Lamy PD, Fuller MD, Anton KE, Mulato AS, Cherrington JM. Miller MD, et al. Among authors: mulato as. J Acquir Immune Defic Syndr. 2001 Aug 15;27(5):450-8. doi: 10.1097/00126334-200108150-00005. J Acquir Immune Defic Syndr. 2001. PMID: 11511821 Clinical Trial.

8

Human renal organic anion transporter 1 (hOAT1) and its role in the nephrotoxicity of antiviral nucleotide analogs.

Cihlar T, Ho ES, Lin DC, Mulato AS. Cihlar T, et al. Among authors: mulato as. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):641-8. doi: 10.1081/NCN-100002341. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563082

9

Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue.

Lee WA, He GX, Eisenberg E, Cihlar T, Swaminathan S, Mulato A, Cundy KC. Lee WA, et al. Among authors: mulato a. Antimicrob Agents Chemother. 2005 May;49(5):1898-906. doi: 10.1128/AAC.49.5.1898-1906.2005. Antimicrob Agents Chemother. 2005. PMID: 15855512 Free PMC article.

10

Suppression of HIV-1 protease inhibitor resistance by phosphonate-mediated solvent anchoring.

Cihlar T, He GX, Liu X, Chen JM, Hatada M, Swaminathan S, McDermott MJ, Yang ZY, Mulato AS, Chen X, Leavitt SA, Stray KM, Lee WA. Cihlar T, et al. Among authors: mulato as. J Mol Biol. 2006 Oct 27;363(3):635-47. doi: 10.1016/j.jmb.2006.07.073. Epub 2006 Aug 2. J Mol Biol. 2006. PMID: 16979654

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